La Société canadienne du sang, le Programme de Recherche en Don et Transplantation du Canada, la Société canadienne de transplantation et le Sir Peter Morris Centre for Evidence in Transplantation ont compilé une liste d’essais cliniques en cours sur la COVID-19 et le don d’organes, la transplantation, l’immunosuppression et autres.
Une équipe de spécialistes de l’information composée de Robin Featherstone, Liset Pengel et Marc-André Simard, a conçu et exécuté une recherche complète entre le 18 et le 21 juin 2020 avec des mots-clé et des termes de vocabulaire combinant des concepts pour COVID-19 / SARS-CoV-2 et transplantation d’organes. Les résultats de la recherche ont été limités aux références publiées depuis 2019. Aucune limite de langue ou de type de publication n’ont été appliqué à la recherche.
Cette liste (en anglais) a été mise à jour le 17 juillet et continuera d’être mise à jour régulièrement.
Mise à jour: 17 juillet, 2020
Title | Author | Abstract | URL |
---|---|---|---|
Maintenance Versus Reduction of Immunosuppression for Renal Transplant Patients Hospitalized With COVID-19 Disease | Brigham, Women's Hospital | Read Abstract | https://clinicaltrials.gov/show/NCT04420364 |
Preventative treatment for patients at risk of COVID-19 infection (PROTECT) | Cambridge University Hospitals, N. H. S. Foundation Trust | Read Abstract | http://www.isrctn.com/ISRCTN88057279 |
AlloSure Guided Immuno-Optimization for COVID-19: An Early Experience | CareDx | Read Abstract | https://clinicaltrials.gov/show/NCT04341103 |
Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Kidney Transplant Patients | Centre Hospitalier Universitaire de Nice | Read Abstract | https://clinicaltrials.gov/show/NCT04369456 |
COVID-19 OUTBREAK AND SOLID ORGAN TRANSPLANTATION (SOT) : AN INTERNATIONAL WEB-BASED SURVEY | Fondazione Policlinico, Universitario Agostino Gemelli IRCCS | Read Abstract | https://clinicaltrials.gov/show/NCT04367896 |
Multicentric Study of Coronavirus Disease 2019 (COVID-2019) in Solid Organ Transplant Recipients | Fundacion Publica Andaluza para la gestion de la Investigacion en Sevilla | Read Abstract | https://clinicaltrials.gov/ct2/show/NCT04319172 |
COVID-19 in Liver Transplant Recipients | Hospital Clinic of Barcelona | Read Abstract | https://clinicaltrials.gov/show/NCT04361591 |
Coronavirus Outcomes Registries in Immunocompromised Individuals Australia (CORIA) | Kirby Institute | Read Abstract | https://clinicaltrials.gov/show/NCT04354818 |
Humoral Immunity Against SARS-CoV-2 in Liver Transplanted Patients in Comparison With Immunocompetent Patients | Magdalena Salcedo | Read Abstract | https://clinicaltrials.gov/show/NCT04410471 |
Impact of the Covid-19 Pandemic on Gastrointestinal and Liver Diseases | Medical University of Graz | Read Abstract | https://clinicaltrials.gov/show/NCT04420637 |
COVID-19 Pandemic and Worldwide Organ Procurement | Paris Translational Research Center for Organ Transplantation | Read Abstract | https://clinicaltrials.gov/show/NCT04416256 |
Observational Study Concerning COVID-19 Infection in Transplanted Kidney, Pancreas or Pancreatic Islet Patients | IRCCS San Raffaele | Read Abstract | https://clinicaltrials.gov/show/NCT04377776 |
Assessment of the Impact of COVID-19 on Transplant Patients and on Patients Awaiting Transplantation | University Hospital, Bordeaux | Read Abstract | https://clinicaltrials.gov/show/NCT04376775 |
Solid Organ Transplant Recipients With Covid-19 French Registry | University Hospital, Strasbourg France | Read Abstract | https://clinicaltrials.gov/show/NCT04360707 |
COVID-19 Research in Organ Transplant Recipients | Vastra Gotaland Region | Read Abstract | https://clinicaltrials.gov/show/NCT04407221 |
Mise à jour: 17 juillet, 2020
Title | Author | Abstratct | URL |
---|---|---|---|
The Effect of Convalescent Plasma Therapy on Patients with COVID-19 | Ardabil University of Medical Sciences | Read Abstract | https://en.irct.ir/trial/47594 |
Adding Colchicine to the Antiretroviral Medication - Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled Trial | Biofarma | Read Abstract | https://clinicaltrials.gov/show/NCT04407208 |
Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: a structured summary of a study protocol for a randomized controlled trial | Christina M Eckhardt, Matthew J Cummings, Kartik N Rajagopalan, Sarah Borden, Zachary C Bitan, Allison Wolf, Alex Kantor, Thomas Briese, Benjamin J Meyer, Samuel D Jacobson, Dawn Scotto, Nischay Mishra, Neena M Philip, Brie A Stotler, Joseph Schwartz, Beth Shaz, Steven L Spitalnik, Andrew Eisenberger, Eldad A Hod, Jessica Justman, Ken Cheung, W Ian Lipkin, Max R O'Donnell | Read Abstract | https://pubmed.ncbi.nlm.nih.gov/32513308 |
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): a structured summary of a study protocol for a randomised, controlled trial | Gorman, E., Shankar-Hari, M., Hopkins, P., Tunnicliffe, W. S., Perkins, G. D., Silversides, J., McGuigan, P., Jackson, C., Boyle, R., McFerran, J., McDowell, C., Campbell, C., McFarland, M., Smythe, J., Thompson, J., Williams, B., Curley, G., Laffey, J. G., Clarke, M., O'Kane, C., McAuley, D. F. | Read Abstract | https://pubmed.ncbi.nlm.nih.gov/32493473 |
Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized Doble Blind 2 Center Trial | Grupo Mexicano para el Estudio de la Medicina Intensiva | Read Abstract | https://clinicaltrials.gov/show/NCT04405310 |
Blood Donor Recruitment During Epidemic of COVID-19 | Guangzhou Blood Center | Read Abstract | https://ClinicalTrials.gov/show/NCT04306055 |
Clinical Use of Stem Cells for the Treatment of Covid-19 | S. B. U. Dr Sadi Konuk Egitim ve Arastırma Hastanesi | Read Abstract | https://clinicaltrials.gov/show/NCT04392778 |
Surgical Activity During the Covid-19 Pandemic: Results for 112 Patients in a French Tertiary Care Center | Hospices Civils de Lyon | Read Abstract | https://clinicaltrials.gov/show/NCT04379232 |
Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | Read Abstract | https://clinicaltrials.gov/show/NCT04416139 |
Umbilical cord blood therapy to prevent progression of COVID-19 related pneumonia: a structured summary of a study protocol for a pilot randomised controlled trial | Malhotra, Atul, Ernest, David, Rogers, Benjamin A., Haylock, David, Watt, Ashalyn, Moeneclaey, Guy, Jenkin, Graham | Read Abstract | https://dx.doi.org/10.1186/s13063-020-04387-y |
Study to Determine the Immunization Status Among Nephrological Health Care Personnel Against SARS-CoV-2 in a Single Center Over the Course of 12 Months | Medical University of, Vienna | Read Abstract | https://clinicaltrials.gov/show/NCT04347694 |
Clinical Study for Human Menstrual Blood-Derived Stem Cells in the Treatment of Acute Novel Coronavirus Pneumonia (COVID-19) | The First Affiliated Hospital, College of Medicine, Zhejiang University | Read Abstract | http://www.chictr.org.cn/showproj.aspx?proj=49146 |
A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID19 Pneumonitis | CCTU-Cancer Theme | Read Abstract | https://clinicaltrials.gov/show/NCT04397471 |
Safety of TY027, a Treatment for COVID-19, in Humans | Tychan Pte, Ltd | Read Abstract | https://clinicaltrials.gov/show/NCT04429529 |
Monocytes and NK Cells Activity in Covid-19 Patients | Universita degli Studi dell'Insubria | Read Abstract | https://clinicaltrials.gov/show/NCT04375176 |
Role of Ibuprofen and Other Medicines on Severity of Coronavirus Disease 2019 | University Hospital, Bordeaux | Read Abstract | https://clinicaltrials.gov/show/NCT04383899 |
Safety and Efficacy of Ruxolitinib for COVID-19 | University of Colorado, Denver | Read Abstract | https://clinicaltrials.gov/show/NCT04348071 |