Canadian Blood Services, the Canadian Donation and Transplantation Research Program, the Canadian Society of Transplantation, and the Sir Peter Morris Centre for Evidence in Transplantation have compiled a list of ongoing clinical trials related to COVID-19 and organ donation, transplantation, immunosuppression, and others.

A team of information specialists, Robin Featherstone, Liset Pengel, and  Marc-Andre Simard, designed and executed a comprehensive search between June 18-21, 2020 with text words and controlled vocabulary terms combining concepts for COVID-19/SARS-CoV-2 and organ transplantation. Search results were limited to references published since 2019. No language or publication type limits were applied to the search.

The following clinical trials were identified during this search.  This list will be regularly updated.

Last updated: July 17, 2020

Download the search strategy here.

Updated: July 17, 2020

Maintenance Versus Reduction of Immunosuppression for Renal Transplant Patients Hospitalized With COVID-19 DiseaseBrigham, Women's HospitalRead Abstract
Preventative treatment for patients at risk of COVID-19 infection (PROTECT)Cambridge University Hospitals, N. H. S. Foundation Trust Read Abstract
AlloSure Guided Immuno-Optimization for COVID-19: An Early ExperienceCareDx Read Abstract
Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Kidney Transplant PatientsCentre Hospitalier Universitaire de NiceRead Abstract
Multicentric Study of Coronavirus Disease 2019 (COVID-2019) in Solid Organ Transplant RecipientsFundacion Publica Andaluza para la gestion de la Investigacion en SevillaRead Abstract
COVID-19 in Liver Transplant RecipientsHospital Clinic of BarcelonaRead Abstract
Coronavirus Outcomes Registries in Immunocompromised Individuals Australia (CORIA)Kirby InstituteRead Abstract
Humoral Immunity Against SARS-CoV-2 in Liver Transplanted Patients in Comparison With Immunocompetent PatientsMagdalena SalcedoRead Abstract
Impact of the Covid-19 Pandemic on Gastrointestinal and Liver DiseasesMedical University of GrazRead Abstract
COVID-19 Pandemic and Worldwide Organ ProcurementParis Translational Research Center for Organ TransplantationRead Abstract
Observational Study Concerning COVID-19 Infection in Transplanted Kidney, Pancreas or Pancreatic Islet PatientsIRCCS San RaffaeleRead Abstract
Assessment of the Impact of COVID-19 on Transplant Patients and on Patients Awaiting TransplantationUniversity Hospital, BordeauxRead Abstract
Solid Organ Transplant Recipients With Covid-19 French RegistryUniversity Hospital, Strasbourg FranceRead Abstract
COVID-19 Research in Organ Transplant RecipientsVastra Gotaland RegionRead Abstract

Updated: July 15, 2020

The Effect of Convalescent Plasma Therapy on Patients with 19-COVIDArdabil University of Medical SciencesRead Abstract
Adding Colchicine to the Antiretroviral Medication - Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled TrialBiofarmaRead Abstract
Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: a structured summary of a study protocol for a randomized controlled trialChristina M Eckhardt, Matthew J Cummings, Kartik N Rajagopalan, Sarah Borden, Zachary C Bitan, Allison Wolf, Alex Kantor, Thomas Briese, Benjamin J Meyer, Samuel D Jacobson, Dawn Scotto, Nischay Mishra, Neena M Philip, Brie A Stotler, Joseph Schwartz, Beth Shaz, Steven L Spitalnik, Andrew Eisenberger, Eldad A Hod, Jessica Justman, Ken Cheung, W Ian Lipkin, Max R O'DonnellRead Abstract
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): a structured summary of a study protocol for a randomised, controlled trialGorman, E., Shankar-Hari, M., Hopkins, P., Tunnicliffe, W. S., Perkins, G. D., Silversides, J., McGuigan, P., Jackson, C., Boyle, R., McFerran, J., McDowell, C., Campbell, C., McFarland, M., Smythe, J., Thompson, J., Williams, B., Curley, G., Laffey, J. G., Clarke, M., O'Kane, C., McAuley, D. F.Read Abstract
Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized Doble Blind 2 Center TrialGrupo Mexicano para el Estudio de la Medicina IntensivaRead Abstract
Blood Donor Recruitment During Epidemic of COVID-19Guangzhou Blood CenterRead Abstract
Clinical Use of Stem Cells for the Treatment of Covid-19S. B. U. Dr Sadi Konuk Egitim ve Arastırma HastanesiRead Abstract
Surgical Activity During the Covid-19 Pandemic: Results for 112 Patients in a French Tertiary Care CenterHospices Civils de LyonRead Abstract
Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranRead Abstract
Umbilical cord blood therapy to prevent progression of COVID-19 related pneumonia: a structured summary of a study protocol for a pilot randomised controlled trialMalhotra, Atul, Ernest, David, Rogers, Benjamin A., Haylock, David, Watt, Ashalyn, Moeneclaey, Guy, Jenkin, GrahamRead Abstract
Study to Determine the Immunization Status Among Nephrological Health Care Personnel Against SARS-CoV-2 in a Single Center Over the Course of 12 MonthsMedical University of, ViennaRead Abstract
Clinical Study for Human Menstrual Blood-Derived Stem Cells in the Treatment of Acute Novel Coronavirus Pneumonia (COVID-19)The First Affiliated Hospital, College of Medicine, Zhejiang UniversityRead Abstract
A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID19 PneumonitisCCTU-Cancer ThemeRead Abstract
Safety of TY027, a Treatment for COVID-19, in HumansTychan Pte, LtdRead Abstract
Monocytes and NK Cells Activity in Covid-19 PatientsUniversita degli Studi dell'InsubriaRead Abstract
Role of Ibuprofen and Other Medicines on Severity of Coronavirus Disease 2019University Hospital, BordeauxRead Abstract
Safety and Efficacy of Ruxolitinib for COVID-19University of Colorado, DenverRead Abstract