Canadian Blood Services, the Canadian Donation and Transplantation Research Program, the Canadian Society of Transplantation, and the Sir Peter Morris Centre for Evidence in Transplantation have compiled a list of ongoing clinical trials related to COVID-19 and organ donation, transplantation, immunosuppression, and others.

A team of information specialists, Robin Featherstone, Liset Pengel, and  Marc-Andre Simard, designed and executed a comprehensive search between June 18-21, 2020 with text words and controlled vocabulary terms combining concepts for COVID-19/SARS-CoV-2 and organ transplantation. Search results were limited to references published since 2019. No language or publication type limits were applied to the search.

The following clinical trials were identified during this search.  This list will be regularly updated.

Last updated: July 17, 2020

Download the search strategy here.

Updated: January 26, 2021

SARS-CoV2 Seroepidemiological Transplanted Subjects (Kidney, Kidney-pancreas, Pancreas, Langerhans Islets)Antonio, Secchi
COVID-19 in Immunosuppressed ChildrenD'Or Institute for, Research
The efficacy and safety of mesenchymal stem cell transplantation in patients with COVID-19 pneumoniaHamedan University of Medical, Sciences
SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian Multicenter StudyHelio Tedesco Silva, Junior
Effect of COvid-19 on Mental Health in Syrian and Turkish Maintenance HemoDialysis Patients: COST-HD StudySisli Hamidiye Etfal, Training
Research, Hospital
Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 InfectionUniversity of California, San Diego
Corona Virus Infection Among Liver Transplant RecipientsDr. Nahed A. Makhlouf, Assiut University
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle EastHamid Al-Essa Organ Transplant Center
Multicenter CTS Pre-and Post-Transplantation Covid-19 Serum StudiesHeidelberg University
Anti-Viral Effects of Voclosporin in COVID-19 Positive Kidney Transplant RecipientsLeiden University Medical Center
Evaluation of short term outcomes of liver transplantation from COVID-19 positive deceased donorsMashhad University of Medical Sciences
Clinical and immunological predictors of SARS-CoV-2 infection and Covid-19 diseases in patients with renal diseases and healthy personsNierenzentrum Heidelberg e.V., Heidelberg Germany
Prevalence and Outcome of SARS-CoV-2 Infection & COVID-19 in Transplant Recipients: The COVITRA StudyUniversitaire Ziekenhuizen, Leuven
Maintenance Versus Reduction of Immunosuppression for Renal Transplant Patients Hospitalized With COVID-19 DiseaseBrigham, Women's Hospital
Preventative treatment for patients at risk of COVID-19 infection (PROTECT)Cambridge University Hospitals, N. H. S. Foundation Trust
AlloSure Guided Immuno-Optimization for COVID-19: An Early ExperienceCareDx
Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Kidney Transplant PatientsCentre Hospitalier Universitaire de Nice
Multicentric Study of Coronavirus Disease 2019 (COVID-2019) in Solid Organ Transplant RecipientsFundacion Publica Andaluza para la gestion de la Investigacion en Sevilla
COVID-19 in Liver Transplant RecipientsHospital Clinic of Barcelona
Coronavirus Outcomes Registries in Immunocompromised Individuals Australia (CORIA)Kirby Institute
Humoral Immunity Against SARS-CoV-2 in Liver Transplanted Patients in Comparison With Immunocompetent PatientsMagdalena Salcedo
Impact of the Covid-19 Pandemic on Gastrointestinal and Liver DiseasesMedical University of Graz
COVID-19 Pandemic and Worldwide Organ ProcurementParis Translational Research Center for Organ Transplantation
Observational Study Concerning COVID-19 Infection in Transplanted Kidney, Pancreas or Pancreatic Islet PatientsIRCCS San Raffaele
Assessment of the Impact of COVID-19 on Transplant Patients and on Patients Awaiting TransplantationUniversity Hospital, Bordeaux
Solid Organ Transplant Recipients With Covid-19 French RegistryUniversity Hospital, Strasbourg France
COVID-19 Research in Organ Transplant RecipientsVastra Gotaland Region

Updated: January 26, 2021

Convalescent Plasma Treatment in COVID-19Aga Khan, University
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1bDeborah, O'Connor
Therapeutic Plasma Exchange for COVID-19-associated HyperviscosityEmory, University
A Phase II, Open Label, Randomized Controlled Trial to Assess the Safety and Efficacy of Convalescent Plasma to Limit COVID-19 Associated Complications in Moderate DiseaseIndian Council of Medical, Research
Efficacy of Convalescent Plasma Therapy in Severely Sick COVID-19 Patients: a Pilot Randomized Controlled TrialInstitute of, Liver
Biliary, Sciences
Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS)Lund University, Hospital
Stem cell therapy in Covid-19Mashhad University of Medical, Sciences
Effect of Allicin derivatives capsule in treatment of patients with new CoronavirusMashhad University of Medical, Sciences
A Phase II, Open Label, Randomized Controlled Trial to Assess the Safety and Efficacy of Convalescent Plasma to Limit COVID-19 Associated ComplicationsMax Super Speciality Hospital, A. Unit of Devki Devi Foundation
COVID-19 Convalescent Plasma Treatment in SARS-CoV-2 Infected Patients: Multicenter Interventional StudyMinistry of Health, Kuwait
Study to Evaluate the Safety and Efficacy of XAV-19 in Patients With COVID-19 Induced Moderate PneumoniaNantes University, Hospital
RAPA-501-Allo Off-the-Shelf Therapy of COVID-19Rapa Therapeutics, L. L. C.
Study of investigational medicinal product CYT107 in patients with COVID-19 infection who have a low level of white blood cells in their blood (ILIAD 7 trial)Revimmune,
A Digital Companion for Loneliness During the COVID-19 Pandemic: a Feasibility StudyThe University of, Auckland
CovidCare 1 - Surveillance and care for confirmed and suspected patients with COVID-19 in general practice: an observational studyUniversitatsklinikum, Heidelberg
Convalescent plasma transfusion therapy in severe COVID-19 patients- a safety, efficacy and dose response study: a structured summary of a study protocol of a phase II randomized controlled trialChowdhury Fr, Hoque A. Chowdhury F. U. H. Amin M. R. Rahim A. Rahman M. M. Yasmin R. Amin M. R. Miah M. T. Kalam M. A. Rahman M. S.
TOGETHER 3 Trial: An Adaptive Randomized Platform Trial to Investigate the Efficacy of Novel Agents for Treatment of SARS-CoV-2 Infection Among High-Risk Outpatient Adults. COVID-19Mark Cotton, Caroline Neal, Eric Decloedt
A Clinical Trial to Assess the Safety and Efficacy of Convalescent Plasma in Severe Covid-19 patientsDr Latha B
Clinical trial to evaluate superiority of anti-SARS-CoV-2 convalescent plasma versus standard-of-care in hospitalized patients with mild COVID-19Hannover Medical, School
Use of Convalescent Plasma in the treatment of COVID-19Hilton Pharma Pvt, Ltd
Convalescent Plasma for Severe COVID-19 PatientsHospital de Clinicas de Porto, Alegre
Efficacy of Convalescent Plasma Therapy in Patients With COVID-19: a Randomized Control TrialInstitute of, Liver
Biliary, Sciences
Evaluation of safety and efficacy of convalescent plasma in COVID-19 patientsInternational Stemcell Services, Ltd
A clinical trial comparing use of convalescent plasma therapy plus standard treatment to standard treatment alone in patients with severe COVID-19 infectionKenyatta University Teaching, Referral and Research Hospital
Study of Coagulation Profile and Role of Heparin Like Effect in Patients With COVID-19Postgraduate Institute of Medical Education and Research
The Effect of Convalescent Plasma Therapy on Patients with 19-COVIDArdabil University of Medical Sciences
Adding Colchicine to the Antiretroviral Medication - Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled TrialBiofarma
Adding Colchicine to the Antiretroviral Medication - Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled TrialDalili, N., Kashefizadeh, A., Nafar, M., Poorrezagholi, F., Firouzan, A., Samadian, F., Samavat, S., Ziaie, S., Fatemizadeh, S
Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: a structured summary of a study protocol for a randomized controlled trialChristina M Eckhardt, Matthew J Cummings, Kartik N Rajagopalan, Sarah Borden, Zachary C Bitan, Allison Wolf, Alex Kantor, Thomas Briese, Benjamin J Meyer, Samuel D Jacobson, Dawn Scotto, Nischay Mishra, Neena M Philip, Brie A Stotler, Joseph Schwartz, Beth Shaz, Steven L Spitalnik, Andrew Eisenberger, Eldad A Hod, Jessica Justman, Ken Cheung, W Ian Lipkin, Max R O'Donnell
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): a structured summary of a study protocol for a randomised, controlled trialGorman, E., Shankar-Hari, M., Hopkins, P., Tunnicliffe, W. S., Perkins, G. D., Silversides, J., McGuigan, P., Jackson, C., Boyle, R., McFerran, J., McDowell, C., Campbell, C., McFarland, M., Smythe, J., Thompson, J., Williams, B., Curley, G., Laffey, J. G., Clarke, M., O'Kane, C., McAuley, D. F.
Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized Doble Blind 2 Center TrialGrupo Mexicano para el Estudio de la Medicina Intensiva
Blood Donor Recruitment During Epidemic of COVID-19Guangzhou Blood Center
Clinical Use of Stem Cells for the Treatment of Covid-19S. B. U. Dr Sadi Konuk Egitim ve Arastırma Hastanesi
Surgical Activity During the Covid-19 Pandemic: Results for 112 Patients in a French Tertiary Care CenterHospices Civils de Lyon
Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Umbilical cord blood therapy to prevent progression of COVID-19 related pneumonia: a structured summary of a study protocol for a pilot randomised controlled trialMalhotra, Atul, Ernest, David, Rogers, Benjamin A., Haylock, David, Watt, Ashalyn, Moeneclaey, Guy, Jenkin, Graham
Study to Determine the Immunization Status Among Nephrological Health Care Personnel Against SARS-CoV-2 in a Single Center Over the Course of 12 MonthsMedical University of, Vienna
Clinical Study for Human Menstrual Blood-Derived Stem Cells in the Treatment of Acute Novel Coronavirus Pneumonia (COVID-19)The First Affiliated Hospital, College of Medicine, Zhejiang University
A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID19 PneumonitisCCTU-Cancer Theme
Safety of TY027, a Treatment for COVID-19, in HumansTychan Pte, Ltd
Monocytes and NK Cells Activity in Covid-19 PatientsUniversita degli Studi dell'Insubria
Role of Ibuprofen and Other Medicines on Severity of Coronavirus Disease 2019University Hospital, Bordeaux
Safety and Efficacy of Ruxolitinib for COVID-19University of Colorado, Denver