Patients with organ or islet transplants live with the life-long possibility of rejection, whereas recipients of HCT face the reverse problem: GVHD (where the newly-transplanted immune system attacks the body). The immunosuppressive medications that keep rejection and chronic GVHD at bay are inadequate and do so by suppressing all immune responses, leaving patients at high risk of infections. These medications are also associated with detrimental side effects such as cardiovascular disease, diabetes, hypertension, renal toxicity and cancer. Patients have identified the inadequacy of current medications and their toxic side-effects as a top research priority.
Patients with organ or islet transplants live with the life-long possibility of rejection, whereas recipients of HCT face the reverse problem: GVHD (where the newly-transplanted immune system attacks the body). The immunosuppressive medications that keep rejection and chronic GVHD at bay are inadequate and do so by suppressing all immune responses, leaving patients at high risk of infections. These medications are also associated with detrimental side effects such as cardiovascular disease, diabetes, hypertension, renal toxicity and cancer. Patients have identified the inadequacy of current medications and their toxic side-effects as a top research priority.

Members Fields of Expertise
Basic Science
Cardiology
Immunology
Infectious Diseases
Nephrology
Pathology

Members Research Interests
Bioinformatics
Epidemiology
Gene Expression Technologies
Genetics & Genomics
Immunoregulation
Laboratory Medicine
Organ Rejection
Proteomics
Transplant Surgery
Virology & Immunology