CDTRP 2026 Research Innovation Grant Competition Results

CDTRP is thrilled to announce the results of the CDTRP 2026 Research Innovation Grant Competition, made possible through our partnership with various esteemed organizations. We are proud to showcase all of the exciting projects that have been funded in this year’s competition.

We would like to extend our warmest congratulations to Dr. Michael Bleszynski and Dr. Nicola Colucci and their team for being awarded the Organ Donation and Transplant Research Foundation of BC/CDTRP Venture Grants. We wish them all the best as they embark on their innovative project!

“Research is the driving force behind progress in organ donation and transplantation. These ODTRF-funded projects showcase the innovative thinking and collaboration needed to advance the field—from improving outcomes for patients undergoing islet cell transplantation to deepening our understanding of the impact of direct contact between donor families and recipients. We are proud to support research that strengthens both the science and the human experience of organ donation and transplantation.“

– Rachael Durie, Co-Chair, Organ Donation and Transplant Research Foundation of BC

Organ Donation and Transplant Research Foundation of BC/CDTRP Venture Grants : Dr. Michael Bleszynski and Dr. Nicola Colucci

Project Title: Eliminating Static Cold Ischemia in Pancreas Preservation: A Pilot Study of Continuous Hypothermic Perfusion from Donor Procurement to Islet Isolation

Main affiliation: University of British Columbia

Theme: 3 – Engineer and Allocate Better Grafts

Lay Abstract

When a pancreas is donated for transplantation, it must be preserved during transport from the donor hospital to the transplant center. Today, this is done by placing the organ on ice. While cooling slows down damage, it does not stop it completely. Much like food kept in a refrigerator, the organ continues to slowly deteriorate over time. For the pancreas, this is especially important because the insulin-producing cells (islets) are very sensitive and can be easily damaged. As a result, many donated pancreases yield too few healthy cells, and patients often need cells from multiple donors to become insulin-free.

This study is testing a new way to better protect the pancreas during this critical period. Instead of placing the organ on ice, we will connect it to a machine immediately after donation that gently pumps a cold, oxygen-rich fluid through it. This keeps the tissue actively supported during the journey, providing vital oxygen and nutrients instead of leaving it to slowly degrade.

We will compare this method to the current standard by studying high-quality pancreases that cannot be used for transplant due to matching issues. We will measure how well the insulin-producing cells function and how healthy they are.

Our ultimate goal is to preserve more viable cells from each donated pancreas. If successful, this approach could reduce the number of donors needed per patient and support better, longer-lasting transplant outcomes.