Depuis 2013, le Programme de recherche en don et transplantation du Canada (PRDTC) soutient la recherche et l’innovation qui s’attaque aux obstacles dans les domaines du don et de la transplantation, dans le but ultime de faire progresser les résultats de santé à long terme ainsi que la qualité de vie des patients canadiens ayant subi une transplantation.
Ci-bas vous trouverez les anciens lauréats du Concours de subventions pour l’innovation en recherche du PRDTC.
Innovation CompetitionFunding partnerFirst NameLast NameProject Title
2023CDTRP UHN Research Innovation GrantMamatha BhatDevelopment of a Machine Learning Tool for Non-invasive Diagnosis of Liver Graft Pathology
2023CDTRP Research Innovation Grant Fédérick D’AragonCINERGY BC: The Calcineurin Inhibitors in NEuRoloGically deceased donors to decrease kidney delaYed graft function (CINERGY)-Pilot randomized controlled trial (RCT)-British Columbia
2023Transplant Research Foundation of BC/CDTRP Venture GrantJagbir GillA unique reciprocity-based strategy to improve living kidney donations in British Columbia: Focus group consultations
2023CDTRP Big Gifts for Little Lives Research Innovation Grant Michael KhouryUtilizing Exercise Cardiovascular and Skeletal Magnetic Resonance Imaging to Evaluate Factors Associated with Cardiorespiratory Fitness in Pediatric Heart Transplant Recipients
2023Transplant Research Foundation of BC/CDTRP Venture GrantJames LanAccelerating the Translation of a Novel Luminex Anti-ABO Antibody Detection Technology to Expand the Use of ABO-Incompatible Transplantation in Canada
2023CDTRP KFOC Research Innovation Grant  Murdoch LeeiesSexual Orientation and Gender Identity in Organ and Tissue Donation and Transplantation (OTDT) A curriculum in cultural competency for OTDT healthcare teams in Canada
2023CDTRP KFOC Research Innovation Grant  Maureen MeadeGuidelines for Sequential Participation of Transplant Recipients into Donor Intervention Trials and Subsequent Transplant Trials
2023Transplant Research Foundation of BC/CDTRP Venture GrantChristopherNguanMachine learning enabled optimization of perioperative hemodynamics in renal transplantation
2023CDTRP SickKids Research Innovation Grant Blayne Amir SayedReduction of proinflammatory damage to limit liver ischemia-reperfusion injury
2023Transplant Research Foundation of BC/CDTRP Venture GrantMypinder SekhonCharacterizing the cerebrovascular physiology of circulatory death during withdrawal of life sustaining therapies in humans
2023CDTRP ATI/Paladin Research Innovation Grant Simon UrschelExploring the lived experience of pediatric heart transplantation from patient and family perspectives
2023CDTRP ATI/Paladin Research Innovation Grant Jason WeatheraldLung Transplantation Research Priority Setting Partnership
2023CDTRP LHSC Research Innovation Grant Charles
eeding an international collaborative to produce guidelines for the conduct of randomized controlled trials of organ donor interventions
Innovation competitionFunding partnerFirst NameLast NameProject title
2022CDTRP UHN Research Innovation GrantNatashaAleksovaA living systematic review and rapid recommendations of the effect of COVID-19 vaccination strategies on outcomes in solid organ transplant recipients
2022Transplant Research Foundation of BC/CDTRP Venture Grant KathrynArmstrongVirtual reality and gameplay as a model for exercise rehabilitation in pediatric solid organ transplant patients. A patient and family led initiative 
2022 CDTRP Research Innovation GrantSuzeBerkhoutTemporalities of Cure:  A qualitative study of psychosocial support needs and long-term survivorship in liver transplantation 
2022CDTRP Research Innovation GrantMarceloCypelEx-vivo immuno-cloaking of donor lungs to prevent transplant rejection: a proof of concept study
2022CDTRP Ontario Health (Trillium Gift of Life Network) Research Innovation GrantIstvanMucsiConfirming the validity of the PROMIS physical function item bank in kidney transplant candidates and recipients
2022CDTRP UdeM Research Innovation Grant Marie-PascalePomeyThe TRANSPLANT-ACTION CONNECTED Graft program (TAC-Graft program)
2022CDTRP KFOC Research Innovation GrantShaifaliSandalExperiencing graft failure and exploring re-transplantation: a patient perspective 
2022CDTRP KFOC Research Innovation GrantSunitaSinghThe efficacy, mechanisms and safety of SGLT2i and GLP1RA combination therapy in kidney transplant recipients: The HALLMARK study 
Innovation competitionFunding partnerFirst NameLast NameProject title
2021CDTRP UdeM Research Innovation GrantChantal BémeurOptimizing post-liver transplantation outcomes: targeting the muscle
2021 CDTRP Research Innovation GrantAmineBenmassaoudDoes a 4-week prehabilitation program improve frailty in patients with cirrhosis undergoing liver transplantation? A feasibility trial
2021CDTRP KFOC Research Innovation GrantTom Blydt-HansenPredictors and Patient Experiences that Enable Access to Care of Post-Traumatic Stress in Pediatric Solid OrganTransplant Recipients
2021Transplant Research Foundation of BC / CDTRP Venture GrantCaigan DuEvaluation of propyl gallate for limitation of cold ischemic injury in organ preservation
2021Transplant Research Foundation of BC / CDTRP Venture GrantDavidHarriman Urine Microbiome Profiling in Kidney Transplant Recipients in Health and Disease
2021CDTRP Research Innovation GrantCorinne
A. Hoesli
Making every pancreatic islet count – engineering a vascularized transplantation system to treat type 1 diabetes
2021CDTRP Research Innovation GrantTania
Virtual home-based pre-habilitation program in lung transplant candidates
2021CDTRP UHN Research Innovation GrantAnaKonvalinkaInvestigating Kidney Tissue Responses to Donor Specific Antibodies in Antibody Mediated Rejection
2021CDTRP Research Innovation GrantMichael KhouryThe MedBIKE™: Evaluating a Novel Telemedicine and Video Game-Linked Exercise Platform for Pediatric Heart Transplant Recipients
2021CDTRP KFOC Research Innovation GrantAmanda Vinson Identifying Sex-Based Disparities in Referral for Transplant, Activation on the Waitlist and Kidney Transplantation
2021CDTRP TGLN Ontario Health Research Innovation GrantCharles WeijerPilot Study to Explore Ethical Issues and Stakeholder Trust in the Use of Normothermic Regional Perfusion in Organ Donation in Canada
2021CDTRP UHN Research Innovation GrantKirsten WentlandtFeasibility of Integrating Patient Reported Outcome Measures and Activity Metrics in a Palliative Care Transplant Program to Improve Function Pre- and Post-Lung Transplant
Innovation competitionFirst NameLast NameGrant title
2019François MartinCarrierEffects of intraoperative hemodynamic management on postoperative outcomes in liver transplantation: a
multicentre prospective observational cohort study
MINDFUL: Mental health IN aDults with cystic Fibrosis who Undergo Lung transplant
2019JenniferConwayEx Situ Heart Perfusion for Optimization of Pediatric Donor Organ Utilization: Attitudes and Perceptions
2019EsméDijkeInto the Unknown: Defining the Optimal Cryopreservation Conditions for Therapeutic Thymic Regulatory T Cells
Prevalence and Incidence of liver disease and access to liver transplant and living liver donation in ethno-racial communities (ACCESS-LT)
2019LakshmanGunaratnamTherapeutic use of recombinant AIM to improve renal transplant outcomes
2019SasanHosseini-MoghaddamMycobacterial Infections in Solid Organ Transplant Recipients (SOTRs) in Ontario from 2002 to 2018
Repopulation of Long Segment Tracheal Allografts for Transplantation
2019CarolineLamarcheBK-specific T-cell immunotherapy; moving towards a clinical trial
2019MeganLevingsDevelopment and validation of a novel assay to quantify alloantigen specific T cells
2019BruceMcManusIdentification of novel cell-specific immunosuppressive therapies from high resolution single-cell RNA sequencing
2019VickyNgLong-Term Outcomes and Health Status of Pediatric Liver Transplant Recipients Off Immunosuppression –
Report from a North American Multi Center Registry
A Novel Ultrasound-based Tool to Assess Muscle Mass in Children With and Without Liver Disease – A Pilot
Feasibility Study
2019IanRogersBuilding Matched Organs using Patient-derived Stem Cells
2019DmitryRozenbergFeasibility of a Home-Based Exercise Program in Liver and Lung Transplant Recipients for Management of Post-Transplant Metabolic Syndrome: A Pilot Randomized Controlled Trial
2019ScottTebbuttInvestigating regulatory T cell gene signature in blood during acute cardiac transplant rejection.
2019SuzanneVercauterenEvaluating the Heterogeneity of T Cell Phenotypes in Pediatric Renal Transplant Recipients: Associations with Patient and Transplant Factors, and Alloimmune Activity
2019DarrenYuenNanobubbles: a new way to non-invasively measure donor kidney ischemia-reperfusion injury
Innovation competitionFirst nameLast nameProject title
2018Samantha JAnthonyinSight: Creation of an Electronic Patient-Reported Outcome Measure Platform in Pediatric Transplantation
2018MamathaBhatDevelopment and Validation of a Practical Web-based Risk Calculator for Post-Transplant Diabetes using Machine learning
2018TomBlydt-HansenInvestigating serum immunometabolomic profiles associated with pediatric kidney and heart transplant alloimmune outcomes
2018EmmanuelleBrochieroFrom the donor to the recipient: Identification of novel biomarkers and therapeutic targets associated with primary graft dysfunction after lung transplantation
2018MichaelChasséEarly detection of potential organ donors using machine learning algorithms compared to traditional epidemiological approaches: Phase 1 of the COMPASS Network
2018BethanyFosterAssociations between Sex Hormone Levels and Immune Profiles among Kidney Transplant Recipients
2018AnneHalpinKnowing the unknown: adding an HLA-specific memory B cell assay to the toolbox.

Acceptability and feasibility of the Kidney Transplant Physical Activity and Social Club (KEeP ACTIVe Club)
2018DeepaliKumarEx-vivo Delivery of Rituximab to Prevent PTLD in EBV mismatch Lung Transplant Recipients: A Pilot Trial
2018MingyaoLiuCystic fibrosis and donor specific injuries in human lung transplants: a comprehensive bioinformatics and systems biology approach
2018DianaMagerBiology of skeletal muscle and sarcopenia in children with ESLD awaiting LTx
2018MaureenMeadeResearch Consent in Donation Trials: A Grounded Theory Pilot Study
2018AllanMurrayApelin receptor signaling and lymphocyte function in allograft rejection
2018MarkusSelznerIndocyanine Green (ICG) Fluorescence imaging during Normothermic Ex Vivo Liver Perfusion (NEVLP) in swine model of Donation after Cardio-circulatory Death (DCD)
2018ShaifaliSandalHealth delivery systems, Health professionals and barriers to living donor kidney transplantation across Canada: a comparative and mixed methods study
2018JasonShahinIs the process of end of life care different for DCD donors vs. non-donors? An exploration of observational data on the process of withdrawal of life sustaining therapies in the intensive care unit.
2018JamesShapiroGene correction in human induced pluripotent stem cells from type-1 diabetic patients by CRISPR/Cas9 genome editing.
Optimizing varicella immunization in children and youth with solid organ transplants to prevent disease and improve long-term health
Innovation CompetitionFirst NameLast NameGrant Title
2017SunitaMathurExploring user-centred design features for e-health applications to support physical activity behaviors in solid organ transplant recipients
2017Marie-JoséeHébertShedding light on Apoptotic exosome like vesicles induced by photopheresis in treatment of
chronic graft-versus-host-disease.
2017GonzaloSapisochinRelationship between 18F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging patterns and circulating tumor DNA to predict hepatocellular carcinoma recurrence after liver transplantation
2017SonnyDhananiExploration of the Impact of Donor Hemodynamics during Donation after Circulatory Determination of Death on Patient and Graft Outcomes in Kidney Recipients
2017AlpSenerThe effect of a mitochondria targeting H2S donor molecules in euthermic (21°C) organ preservation using existing organ preservation solutions.
2017KevinWenPhased Implementation for Feasibility and Evaluation of an Adherence Monitoring, Feedback, and Individualized Intervention System for Improving Immunosuppression Medication Adherence in Kidney Transplant Recipients
2017PuneetaTandonA personalized online pre-habilitation program to improve health outcomes in patients awaiting liver transplantation
2017BenjaminAdamThe molecular phenotype of polyomarivus nephropathy and its distinction from T-cell mediated rejection
2017StevenGreenwayMechanism of Microbiome-Mediated Gastrointestinal Toxicity of Mycophenolate Mofetil
2017AldoMontano-LozaA prospective, longitudinal evaluation of skeletal muscle for prognosis of patients with cirrhosis evaluated for liver transplantation
2017TerezaMartinuTargeting the renin-angiotensin system to monitor and treat fibrosis in chronic lung allograft dysfunction
Innovation CompetitionFirst NameLast NameGrant Title
2016LakshmanGunaratnamKidney Injury Molecule-1 (KIM-1) gene polymorphisms and risk of delayed graft function after deceased donor kidney transplantation
2016AndrzejChruscinskiNon-HLA Antibodies in Heart Transplantation: Profiling with Antigen Microarrays
2016StevenParaskevasCirculating extracellular vesicles as markers of beta-cell stress and injury after islet transplantation
2016JenniferReedCardiovascular Prehabilitation in Patients Awaiting Heart Transplantation - Addressing Clinical Needs (PREHAB HTx Study)
2016SharonChihBiomarker Discovery for Validation in Cardiac Allograft Vasculopathy: BIOCAV pilot study
2016JayanNagendranMolecular quantification of tissue injury and repair pre, during, and post ex-vivo perfusion of swine lung transplants
2016FaisalKhanGene Variants Influencing Complement-Dependent Cytotoxicity (CDC) and Antibody-Dependent Cellular Cytotoxicity (ADSS) as Predictors of Antibody Mediated Rejection (AMR) after Kidney Transplantation
2016SimonUrschelAerobic capacity, muscle strength, and muscle endurance after pediatric transplantation
2016Constantine KarvellasPrognostic impact of Liver Fatty Acid Binding Protein in Acute Liver Failure
2016IstvanMucsiPsychosocial and Ethno-Cultural Barriers to Living Donor Kidney Transplantation- Qualitative Study
2016MamathaBhatCharacterization of the Intestinal Microbiome and its Role in Diabetes after Transplantation
2016HéloïseCardinalAccepting or refusing a kidney from a deceased donor: can mathematical optimization and machine learning help shared decisionmaking to make the right choice for each individual patient?
2016EmmanuelleBrochieroIdentification of novel markers and therapeutic targets associated with ischemia/reperfusion injury and primary graft dysfunction in lung transplants.
2016Jean-FrançoisCailhierDeciphering the monocyte and immune activation in brain dead donors: A role for MFG-E8?
2016SamanthaAnthonyMEASURING WHAT MATTERS: Integrating Patient-Reported Outcomes into Clinical Practice
Innovation competitionFirst NameLast NameGrant title
2015SimonFrédéric DufresneA comprehensive model to predict the risk of invasive aspergillosis after hematopoietic stem cell transplantation.
2015ToddLowary“Evaluation of a glyconanotechnology tool for personalized ABO-incompatible kidney transplantation”
2015BanusSisA 34-gene signature diagnostic test to determine the individualized likelihood of antibody-mediated rejection and kidney transplant failure using formalin-fixed, paraffin-embedded biopsy samples: a multicenter external validation study
2015LoriWestCharacterization of Donor Specific Immune Reactivity in Pediatric Heart Transplant: Impact of Thymectomy
2015MarkusSelznerRocuronium and Midazolam Metabolomics for the Assessment of Liver Grafts during Subnormothermic Ex Vivo Liver Perfusion
2015JoséeBouchardBrain-dead donor management goals, donor biomarkers and the development of delayed graft function in kidney transplant patients
Innovation competitionFirst NameLast NameGrant Title
2014Jean-SébastienDelisle“Optimizing autologous anti-EBV T-cell lines from seronegative patients for adoptive immunotherapy; a pre-clinical study”
2014NowellFineDetection of Cardiac Allograft Vasculopathy
Using Myocardial Contrast Perfusion Imaging: A Multicenter Study in Adult and Pediatric
Transplant Recipients
2014GiadaSebastianiNon-invasive diagnosis of nonalcoholic steatohepatitis in liver transplant recipients: a prospective, longitudinal study employing serum citokeratin 18 and transient elastography