Repopulation of Long Segment Tracheal Allografts for Transplantation

The generation of bioengineered tissues and organs is an exciting field of research which in the future, can possibly lead to a new source of grafts for transplantation. Using biological scaffolds and recipient-derived stem cells, we aim to generate bioengineered tracheas for eventual transplantation. Importantly, the use of recipient’s own cells would prevent rejection and eliminate the need for immune suppression significantly increasing patient quality of life. This has wide implications for not only tracheal transplantation but across all solid organs.