The CDTRP Platforms consolidate new and emerging tools offered at the national level to meet the needs of the research community and promote cohesion across all areas of donation and transplantation. The three platforms provide resources and tools to support existing and future projects across the five research Themes.
Clinical Trial Design and Support
The CDTRP can connect investigators to the right experts for advice in designing and running clinical trials, including access to methodological support, contract research organization, support identifying contacts at sites for multisite studies, and facilitating a review panel for a trial protocol.
Clinical studies can request use of the CDTRP’s independent Data Safety Monitoring Board (DSMB) to help monitor progress and adverse events and provide arms-length advice on patient safety and trial accrual. The DSMB comprises 7 voting members that independently review and evaluate study data for participant safety, study conduct and progress, and recommend continuation, modification or termination.
Economic, Ethical, Legal and Social (EELS) Support
The CDTRP counts on a group of experts to examine the economic, ethical, legal and social (EELS) issues that are major components of the donation and transplant landscape, including pro-active support to inform the direction of biomedical, clinical and population health studies.
CDTRP National Specimen Inventory (NanSI)
Biological samples and research data collected in Canada representing phenotypes, genotypes, treatment processes, and patient outcomes have great potential to transform biological and clinical research. The CDTRP is working with its institutional partners to integrate this national infrastructure through a secure and user-friendly interface, linking organ and stem cell donation, solid organ transplant and hematopoietic cell transplant (HCT) data and samples collected by CDTRP investigators.
Management Resources, Small Meeting Support, and Connections to Expertise
Throughout a project’s life, the CDTRP Management Team can offer logistics support, including the organization of teleconferences, webinars, face-to-face meetings (when possible) and provide support for national collaboration building. We can help organize small research meetings with meeting space and technical support. We offer access to our communication platforms for team meetings, including webinars, zoom meetings, and our file-sharing system.
We can facilitate connections with experts in donation and transplantation research areas and complementary disciplines from across Canada and internationally. These include:
- Biomarkers, Immune Monitoring
- Artificial Intelligence
- Patient-reported outcome measures (PROMs)
Communication and Knowledge Translation Support
We can assist with communication of your project to the community through our monthly Theme calls and Annual Scientific Meeting. For public and cross-disciplinary outreach, we can coordinate the development, translation (French/English), and dissemination of a FAST FACTS document on your research topic. Project outputs can be shared via our diverse communication channels, including social media, and educational materials and resources developed for patients, families and donors can be shared through the CDTRP Patient Portal.