CDTRP KFOC Research Innovation Grant – Dr. Shaifali Sandal

Through collaboration with partner organizations, CDTRP is pleased to announce the results of our annual Research Innovation Grant competition to fund exciting new project ideas. We are happy to highlight all of the projects funded in the 2022 competition.

CDTRP KFOC Research Innovation Grant

Dr. Shaifali Sandal

  • Main affiliation: McGill University Health Centre
  • Theme 5 – Restore Long-Term Health
  • Title: Experiencing graft failure and exploring re-transplantation: a patient perspective

Lay abstract

Kidney transplantation can significantly improve the lives of patients with kidney disease. But the life span of a transplanted kidney is limited, and many patients experience graft failure. Patients with graft failure do extremely poorly. They experience a life-altering event for which they are often poorly prepared and poorly supported. Many are not re-transplant candidates and some die after experiencing graft failure. It is known that patients with graft failure experience fragmented transitions of care between the transplant and dialysis teams. Patient perspectives are poorly researched and poorly understood, thus poorly translated into clinical practice.

This research project aims to obtain the perspectives of patients and their caregivers who are in different stages of graft failure. We want to describe the unique experiences and needs of patients in different stages of graft failure. We also want to identify factors that can improve the care, outcomes, and well-being of these patients and what patients think impedes their access to re-transplantation. We will use well-established qualitative methods that are largely unexplored in the field of kidney transplantation. Our team includes nationally recognised transplant clinicians, researchers, and leaders.

With this project, we hope to generate data that can help develop outcome measures that matter to the patient and their caregivers. Our future work will also entail developing guidelines to improve the care of patients with graft failure. Overall, we want to improve the outcomes and well-being of patients with graft failure and identify patient-level barriers to re-kidney transplantation.