CDTRP UHN Research Innovation Grant awardee – Feasibility of Integrating Patient Reported Outcome Measures and Activity Metrics in a Palliative Care Transplant Program to Improve Function Pre- and Post-Lung Transplant (Kirsten Wentlandt)
Through collaboration with partner organizations, CDTRP is pleased to offer our annual Research Innovation Grant competition to fund exciting new project ideas. Over the coming weeks, we will be profiling all of the projects funded in the 2021 competition.
Funded through a CDTRP UHN Research Innovation Grant:
Title: Feasibility of Integrating Patient Reported Outcome Measures and Activity Metrics in a Palliative Care Transplant Program to Improve Function Pre- and Post-Lung Transplant
- Principal investigator: Kirsten Wentlandt
- Main affiliation: University Health Network
- Part of Theme 5
- Team: Dmitry Rozenberg, Lisa Wickerson, Istvan Mucsi, Tania Janaudis Ferreira, Tara Lohmann
Background: Lung transplant (LTx) candidates often experience symptoms such as shortness of breath (SOB)and cough, as well as reduced quality of life and physical function. At University Health Network, a palliative care (PC) clinic was established to help patients with these symptoms, and to improve their quality of life and overall function.
Aims: The aim of our study is to determine if we can properly evaluate the PC clinic with standardized patient surveys (PROMs) and activity trackers. We plan to see how common PC tools will relate to the PROMs and the activity trackers (Fitbits). Finally, we want to ask LTx patients about their experiences attending the PC program, and their use of opioids, medications commonly used by PC clinicians to manage cough and SOB.
Methods: We will study 40 LTx candidates and collect their PROMs and activity metrics 2 weeks prior to the patient’s PC clinic visit, during their first clinic visit, and repeated every 4-6 weeks. The use of opioids will be monitored before transplant and up to 3 months post-transplant. We will interview 8 patients pre-transplant and 12 patients post-transplant. We will explore patient views on the benefits of PC, their experiences with the PROMs, the Fitbits, and using opioids.
Significance: This project will be the first study of a PC clinic in pre-transplant lung population and will help us determine how best to enhance the benefits of the PC clinic. This will also allow multi-center collaborations and clinical trials to assess PC interventions in other transplant populations.