This rich program has been developed by the CDTRP Annual Scientific Meeting Planning Committee, co-chaired by Lorraine Hamiwka (Theme 5) and Marat Slessarev (Themes 1 & 2) and with feedback from the CDTRP community and Theme leads. Other members of the Planning Committee include:

  • Sabine Ivison (Themes 4 & 5)
  • Warren Fingrut (Themes 1, 2 & 3)
  • Vanessa Silva e Silva (Themes 1 & 2)
  • Nicholas Murphy (Trainee, Theme 2)
  • Ke Fan Bei (PFD partner, Themes 1, 3 & 4)
Register here for the Annual Scientific Meeting
Please note the following schedules are in Eastern Standard Time (EST)

PRE CDTRP ANNUAL SCIENTIFIC MEETING EVENTS

TUESDAY, DECEMBER 7, 2021

Deceased Donation Stream

On December 7, the CDTRP is partnering with the Critical Care Canada Forum, Trillium Gift of Life Network/Ontario Health and Canadian Blood Services to support the Deceased Donation Stream of the 2021 virtual Canadian Critical Care Forum.

We are excited to spotlight major CDTRP initiatives and provide a forum for our members to propose new collaborations and discuss future opportunities for individual projects and the overall CDTRP network.    

Click here to see the Deceased Donation Stream Program
Register here
Women in Donation – A Women in Transplantation Event 

Women in Transplantation (WIT) programming and events have covered many critical issues over the last decade, including a focus on gender in careers in transplantation. This will be the first WIT event related to the careers of women specifically involved in donation. Presentations will highlight their career trajectories (e.g., how they became interested in the field, how it fits into their larger view of their work and essential issues that they think are important.) 

This virtual event will include an overview of the Women in Transplantation initiative and several short presentations from Women in Donation (personal stories about experiences, challenges, opportunities), followed by open discussion and Q&A.

Speakers:
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CDTRP ANNUAL SCIENTIFIC MEETING

WEDNESDAY, DECEMBER 8, 2021

Block 1: COVID-19 and Donation and Transplantation: What We Have Learned

COVID-19 has impacted all aspects of transplantation and transplant recipients are at risk of severe disease. Dr. Kumar will provide an overview of what we know about new therapies such as monoclonal antibodies and antivirals for COVID-19 and their use in transplantation. Donors are required to be screened for COVID-19 and the potential for use of organs from COVID-19 donors will be discussed.  The immune response and effectiveness of COVID-19 vaccine in transplant candidates and recipients will also be presented. 

Dr. Kumar’s presentation will be followed by three short presentations from individuals with different lived experiences and perspectives in organ donation and transplantation (Organ Procurement Organization, Donation Coordinator, transplant family). A thirty-minute panel discussion will then focus on lessons learned over the course of the COVID-19 pandemic.  

Moderator: Sam Shemie
Speakers and panelists:
Time (EST)ContentSpeaker
11:00-11:10WELCOME REMARKSLorraine Hamiwka & Marat Slessarev
11:10 - 11:15Introduction: Block 1 - COVID-19 and Donation and Transplantation: What We Have LearnedSam Shemie & Guillaume Maitre
11:15 - 11:45The Art and Science of COVID-19 in Transplantation
Details
Deepali Kumar
11:45 - 12:00Q&ADeepali Kumar
12:00 - 12:15BREAK
12:15 - 12:30COVID and ODOs – How Canadian ODOs came together to ensure safety in the systemMatthew Weiss
12:30 - 12:40Organ Donation in BC - Adapting to a Pandemic
Details
Bobbi Paquette
12:40 - 12:50Life as a Transplant Family during Covid
Details
Lindsey Kemp
12:50 - 13:20Panel Discussion: Lessons LearnedMatthew Weiss, Bobbi Paquette, Lindsey Kemp, Andrew Healey & Louis Beaulieu
Moderator: Kristina Krmpotic
Speakers:
Time (EST)ContentSpeaker
14:30 - 14:35IntroductionKristina Krmpotic
14:35 - 14:40Alterations in muscle fiber types in children with end-stage liver disease undergoing liver transplantation
View abstract
Amber Hager
14:40 - 14:45A Qualitative Descriptive Study of Kidney Transplant Recipients Who Experience Graft Loss: A Forgotten Cohort
View abstract
Anna Horton
14:45 - 14:50Regulatory T cell biomarkers identify patients at risk of developing acute cellular rejection in the first year following heart transplantation
View abstract
Ji-Young Kim
14:50 - 14:55Impact of ApoExo vesicules and Anti-LG3 autoantibodies derived from vascular damage on microvascular depletion, fibrosis and renal dysfunction in the context of lupus nephretis
View abstract
Marie-Hélène Normand
14:55 - 15:00
Donor-Recipient Weight Mismatch as a Risk Factor for Delayed Graft Function in Renal Transplantation
View abstract
Faisal Jarrar
15:00 - 15:05AutoKV-Net: Calculating Single Kidney Volume in Two-Dimensional Ultrasound Automatically by Mimicking Sonographers
View abstract
Rohit Singla
15:05 - 15:30Q&AAmber Hager, Anna Horton, Ji-Young Kim, Marie-Hélène Normand, Faisal Jarrar & Rohit Singla
Block 2: International Research and Training in Donation and Transplantation: Barriers and Opportunities

This block will feature two presentations from CDTRP Members, one who has completed a large international study in a donation and one planning a large international study in transplantation. Further presentations from international trainees will focus on the challenges and opportunities they have experienced. These presentations will be followed by a panel discussion about barriers and opportunities for international collaborations. 

Moderators: Vanessa Silva e Silva & Lori West
Speakers and panelists:
Time (EST)ContentSpeaker
15:40 - 15:45Introduction Block 2 - International Research and Training in Donation and Transplantation: Barriers and OpportunitiesVanessa Silva e Silva & Lori West
15:45 - 15:55Home-based exercise for solid organ transplant patients and people with chronic disease: A shift from Brazil to Canada
Details
Manoela Ferreira
15:55 - 16:05Increase International Research Collaborations through international mobility of interns: Mitacs GRA ProgramÉtienne Pineault
16:05 - 16:25Panel discussionManoela Ferreira, Étienne Pineault & Jennifer Raven
16:25 - 16:35BREAK
16:35 - 16:40IntroductionVanessa Silva e Silva & Lori West
16:40 - 16:50How to organize multinational initiatives - barriers and facilitators (Transplantation)John Gill
16:50 - 17:00How to organize multinational initiatives - barriers and facilitators (Donation)Sonny Dhanani
17:00 - 17:10International Clinical Trials: Perspectives from a funder
Details
Brian Rowe
17:10 - 17:50Panel Discussion John Gill, Arthur J. Matas, Sonny Dhanani & Brian Rowe

CDTRP Trainees and Planning Committee Members Dr. Nicholas Murphy and Dr. Vanessa Silva e Silva are organizing trainee working sessions. The purpose of these sessions is to discuss and plan for a trainee-led publication focused on an important and underexplored research topic.

Day one: Orientation session. Trainees will introduce themselves, their main research areas, expertise, and research experience.

THURSDAY, DECEMBER 9, 2021

Block 3: Point and Counterpoint: Normothermic Regional Perfusion 

The use of normothermic regional perfusion (NRP) in controlled donation after circulatory determination of death (cDCDD) is an established practice in several European countries. NRP is thought to improve organ viability and function by reversing ischemic injury sustained during the dying process in cDCDD donors. However, numerous ethical questions and empirical uncertainties suggest a cautious approach to NRP’s implementation in Canada. Policymakers are now considering whether the use of NRP is appropriate for the Canadian context, with a program of research aiming to assess its safety, efficacy, and feasibility underway. This point-counterpoint discussion will familiarize attendees with the logistical, empirical, and ethical challenges of implementing NRP in Canada, and assess the pros and cons of moving ahead with the technology’s use. The subsequent panel discussion will probe these issues in more detail, and feature the perspectives of stakeholders from Canada and the UK.  

Moderators: Kimia Honarmand & John Basmaji
Speakers and panelists:
Time (EST)ContentSpeaker
11:00 - 11:05Welcome RemarksLorraine Hamiwka & Marat Slessarev
11:05 - 11:15Introduction: Block 3: Point and Counterpoint: Normothermic Regional Perfusion Kimia Honarmand
& John Basmaji
11:15 - 11:45Point - CounterpointPoint: Anton Skaro; Counterpoint: Andrew Healey
11:45 - 12:15Panel DiscussionAndrew Healy, Anton Skaro, Alex Manara, Laurie Blackstock & Sam Shemie
12:15 - 12:25BREAK
Block 4: Antemortem Interventions

Antemortem interventions in controlled donation after circulatory determination of death (cDCDD) are commonly used in cDCDD donors to improve organ viability and to enhance the likelihood of successful donation. Despite their widespread use, robust empirical evidence on safety and efficacy is lacking for several interventions. Calls for well-designed randomized controlled trials (RCTs) to assess antemortem interventions are beginning to appear in the literature. However, because cDCDD donors will still be alive at the time of the intervention, these trials pose ethical and logistical challenges which eclipse those faced in the context of deceased donor intervention research. This discussion will familiarize attendees with the ethical and logistical challenges of cDCDD RCTs, and discuss possible approaches to tackling them. The subsequent panel discussion will feature local and international perspectives, and assess the best approaches to moving towards this next frontier of donor intervention research.

Moderator: Nicholas Murphy
Speakers and panelists:
Time (EST)ContentSpeaker
12:25 - 12:30 Introduction: Block 4 - Antemortem InterventionsNicholas Murphy
12:30 - 12:40Randomized controlled trials in donation after circulatory death: Understanding the obstacles and moving forward
Details
Frédérick D'Aragon
12:40 - 12:55Ethico-legal challenges of antemortem interventions
Details
Henrietta Consolo
12:55 - 13:10Ethical challenges in RCTs of antemortem interventions
Details
Charles Weijer
13:10 - 13:40Panel Discussion Frédérick D'Aragon, Charles Weijer, Henrietta Consolo & Heather Talbot
Block 5: Donor – Recipient Meeting: Ethics, Law, Systems, and Human Stories

This block will contain four ten-minute presentations followed by a thirty-minute panel discussion.  

The presentations will include:  

  1. Story of a donor and recipients who found each other 
  2. Ethical issues and legal considerations, risks and benefits 
  3. Perspectives from an organ procurement organization 
Moderator: Aviva Goldberg
Speakers and panelists:
Time (EST)ContentSpeaker
14:10 - 14:20WELCOME AND AFTERNOON INTRODUCTIONSLorraine Hamiwka & Marat Slessarev
14:20 - 14:25Introduction: Block 5 - Donor - Recipient Meeting: Ethics, law, systems, and human storiesAviva Goldberg
14:25 - 14:35A Shared Heart
Details
Kim LeBlanc & Dave Allingham
14:35 - 14:45Surviving HLH: inclusion saves lives
Details
Susan Doherty
14:45 - 14:55When the donor met the recipient: the ethical issues
Details
Marie-Chantal Fortin
14:55 - 15:05Exploring the legal and policy frameworks governing information disclosure between donor families and transplant recipients
Details
Vanessa Gruben
15:05 - 15:15
OPO Perspective - Title TBC
Details
Michael Ward
15:15 - 15:45Panel Discussion Kim LeBlanc, Dave Allingham, Susan Doherty, Marie-Chantal Fortin, Vanessa Gruben & Michael Ward
15:45 - 15:55BREAK
Block 6: Focus on Donation and Transplantation in Underserved Populations

This block will include six short presentations from trainees whose work focuses on donation and transplantation in underserved populations, followed by a presentation from CDTRP member Dr. Istvan Mucsi entitled “Barriers to Accessing Kidney Transplantation Among Populations Marginalized by Race and Ethnicity in Canada”.  

Moderator: Warren Fingrut & Gabriele Jagelaviciute
Speakers:
Time (EST)ContentSpeaker
15:55 - 16:00Introduction: Block 6 - Focus on Donation and Transplantation in Underserved PopulationsWarren Fingrut & Gabriele Jagelaviciute
16:00 - 16:05Black Donors Save Lives: Multimedia resources developed in collaboration with Black People
to engage their communities as potential stem cell donors
View abstract
Sylvia Okonofua
16:05 - 16:10Saving Lives with Pride: Development and Evaluation of Multimedia Resources to Engage Gay, Bisexual, and Queer Men in Canada as Stem Cell Donors
View abstract
Rupal Hatkar
16:10 - 16:15Development and Evaluation of a Library of TikToks to Support the Recruitment of Committed Hematopoietic Stem Cell Donors from Needed Demographic Groups
View abstract
Brady Park
16:15 - 16:20Development of multimedia tools to engage East Asian Peoples in Canada as hematopoietic stem cell donors
View abstract
Lauren Sano
16:20 - 16:25
Understanding the barriers to accessing Living Donor Kidney Transplantation in the African, Caribbean, and Black community
View abstract
Princess Okoh
16:25 - 16:50Q&ASylvia Okonofua, Rupal Hatkar, Brady Park, Lauren Sano & Princess Okoh
16:50 - 16:55IntroductionWarren Fingrut & Gabriele Jagelaviciute
16:55 - 17:25Barriers to Accessing Kidney Transplantation/Living Donor Kidney Transplant Among Populations Marginalized by Race and Ethnicity in Canada + Q&A
Details
Istvan Mucsi
17:25 - 17:35CLOSING REMARKSLorraine Hamiwka & Marat Slessarev

CDTRP Trainees and Planning Committee Members Dr. Nicholas Murphy and Dr. Vanessa Silva e Silva are organizing trainee working sessions. The purpose of these sessions is to discuss and plan for a trainee-led publication focused on an important and underexplored research topic.

Day two: An overview of potential topics to be explored, identification of interest, planning next steps and timeline.

FRIDAY, DECEMBER 10, 2021

Moderator: Mélanie Dieudé
Speakers
Time (EST)ContentSpeaker
11:00 - 11:10WELCOME REMARKSLorraine Hamiwka & Marat Slessarev
11:10 - 11:20Mapping the Canadian Donation and Transplantation Research and Innovation EcosystemAndriy Strogan
11:20 - 11:30Canadian Research Networks: Emerging National and International Funding OpportunitiesStephen M. Robbins
11:30 - 11:55DiscussionAndriy Strogan & Stephen M. Robbins
Block 7: Advances in Immunology and Cell Therapy

This block will highlight advances in Immunology and Cell Therapy. It will feature two fifteen-minute presentations followed by a question-and-answer session.   

Moderators: Sabine Ivison & Ke Fan Bei
Speakers: 
Time (EST)ContentSpeaker
11:55- 12:00Introduction: Block 7 - Advances in Immunology and Cell TherapySabine Ivison & Ke Fan Bei
12:00 - 12:15Cell Therapy Presentation - Title TBCKevin Hay
12:15 - 12:30Cell surface engineering of the endothelial glycocalyx for prevention of transplant rejection
Details
Jonathan Choy
12:30 - 12:45Q&AKevin Hay & Jonathan Choy
Block 8: Mental Health in Donation and Transplantation

This block will contain three ten-minute presentations followed by a thirty-minute panel discussion.  

Two presentations will be from Theme 5 CDTRP Mental Health and Wellness Hub members, and one will come from Theme 1 focused on donor coordinator burnout. The panel discussion will include perspectives from adult recipients and caregivers.  

Moderators: Samantha Anthony & Tatsuma Hind
Speakers and panelists:
Time (EST)ContentSpeaker
13:15 - 13:20Introduction: Block 8 - Mental Health in Donation and TransplantationSamantha Anthony & Tatsuma Hind
13:20 - 13:30Frictions in the Transplant Clinic: Using Ethnography and Arts to Understand Challenges Across the Span of Solid Organ Transplantation
Details
Suze Berkhout
13:30 - 13:40Does having a pet impact mental health and lifestyles habits?
Details
Isabelle Doré
13:40 - 13:50The BRiC Program: Understanding work-related issues among organ donation coordinators
Details
Vanessa Silva e Silva
13:50 - 14:20Panel Discussion Suze Berkhout, Isabelle Doré, Vanessa Silva e Silva, Sandra Holdsworth & Mary Smith
14:20 - 14:30CLOSING REMARKSLori West, Lorraine Hamiwka & Marat Slessarev