
CDTRP 2025 Research Innovation Grant Competition Results
CDTRP is thrilled to announce the results of the CDTRP 2025 Research Innovation Grant Competition, made possible through our partnership with various esteemed organizations. We are proud to showcase all of the exciting projects that have been funded in this year’s competition.
We would like to extend our warmest congratulations to Dr. Vikas Srinivasan Sridhar and his team for being awarded the Organ Donation and Transplant Research Foundation of BC/CDTRP Venture Grant. We wish them all the best as they embark on their innovative project!
“We are proud to support these bold and innovative projects that address critical gaps in organ donation and transplantation research. From improving neurologic death prediction to advancing organ viability through perfusion science and elevating patient and physician voices in kidney transplantation, each project reflects our commitment to discovery, collaboration, and meaningful impact.”
Rachael Durie, ODTRF Co-Chair
Organ Donation and Transplant Research Foundation of BC/CDTRP Venture Grant: Dr. Vikas Srinivasan Sridhar
Project Title: Patient and Physician Perspectives on Cardio-Kidney-Metabolic therapies in Kidney Transplantation
Main affiliation: University of British Columbia
Theme: 5 – Restore Long-Term Health
Lay Abstract
Kidney transplant recipients (KTR) often face significant health challenges, including heart and kidney problems. New treatments, such as sodium-glucose cotransporter inhibitors (SGLTi), glucagon-like peptide 1 receptor agonists (GLP1RA), and nonsteroidal mineralocorticoid receptor antagonists (nsMRA), have shown promise in improving heart and kidney health. These therapies act through different mechanisms, so combined, they may provide greater improvements and benefits than using any one treatment alone. However, these treatments are still emerging, and it is not yet clear how they work together or what the best approach is for using them in KTRs. The goal of this study is to explore which factors are most important to KTRs and doctors when considering the combined use of all these treatments within the first several months after kidney transplant. These factors could include concerns about potential side effects, how well the treatments work together, or how they fit into the daily lives of transplant recipients. By gathering input from both KTRs and healthcare providers, the study hopes to better understand how to make treatment decisions that will improve patient health and quality of life. Ultimately, the findings from this study could guide future clinical trials of these treatment, and help doctors and patients make more informed choices about managing heart and kidney complications after a kidney transplant. Understanding the preferences and needs of KTRs is essential for developing personalized, effective treatment strategies that benefit both their short-term and long-term health.