The Forum’s publications and Domain summaries: enhancing organ and tissue donation systems
To identify and address common challenges in deceased organ and tissue donation, Transplant Québec and the Canadian Donation and Transplantation Research Program (CDTRP) organized The International Donation and Transplantation Legislative and Policy Forum. The Forum produced 94 evidence-informed expert consensus recommendations to improve organ and tissue donation and transplantation laws and policies. These aspirational recommendations can be adapted for use in donation and transplant systems in Canada and around the world. You can access the Forum’s publications in Transplantation Direct below and download all Domain summaries.
The CDTRP is leading knowledge mobilization efforts to support the implementation of recommendations. To stay informed about The Forum’s ongoing initiatives, we invite you to explore our revamped Forum website. This is where you can access direct links to The Forum’s publications, summaries of recommendations in each domain, fact sheets, and presentations by Dr. Matthew Weiss.
DOMAIN 1: Baseline Ethical Principles
The Baseline Ethical Principles domain proposes an ethical framework to assist stakeholders and decision-makers in incorporating ethical principles into OTDT practice and policy to maintain public trust and integrity.
The domain acknowledged the importance of international standards of baseline ethical principles within OTDT regulations, policies, and legislation, as outlined in the World Health Organization (WHO) Guiding Principles, the Declaration of Istanbul, and the Barcelona Principles. What is less well-established is how to evaluate newly proposed practices or programs according to these principles.
The proposed framework will assist those responsible for making and approving ethical policy decisions consistent with the established international agreements, declarations, and resolutions on the ethical underpinnings of an OTDT system.
DOMAIN 2: Legislation and Policy
The Legislation and Policy domain provides expert guidance for legislative and policy reform. The 12 recommendations outlined in the chapter focus on (1) legal definitions and legislative scope; (2) consent requirements for donation; (3) allocation of organs and tissue; (4) operation of OTDT systems; and (5) travel for transplant and organ trafficking.
Given that OTDT systems vary in how they are regulated, and local cultural, social, and economic factors impact law and policy, the 12 recommendations address fundamental issues in OTDT. Thus, the recommendations could apply wholly or in part to any jurisdiction developing or reforming its system.
DOMAIN 3: Organ Donation Organization Architecture
The Organ Donation Organization Architecture domain provides expert guidance on the components of an effective organ donation organization (ODO), its relationship with OTDT stakeholders, and markers of best practices supporting an effective donation and transplantation care pathway and continuous improvement.
The 33 recommendations represent the foundational markers of a safe, fair, and transparent system that maximizes the number of organs available for transplantation and maintains public trust across all stages of the care pathway.
DOMAIN 4: Organ and Tissue Donation Consent Model and Intent to Donate Registries
The Organ and Tissue Donation Consent Model and Intent to Donate Registries domain provides expert guidance for jurisdictions implementing or reforming their consent model. The consent model working group does not recommend one type of consent model over another.
Instead, the 11 recommendations outlined in this domain discuss the main factors influencing the success of a consent model. These factors include the type of consent model (opt-in vs opt-out), donor registry, marketing campaigns/public education, and the education of healthcare professionals.
DOMAIN 5: Living Donation
Coming soon.
DOMAIN 6: Tissue and Cell Donation
The Tissue and Cell Donation domain provides expert legislative and policy reform guidance. The 13 recommendations outlined in the chapter focus on (1) self-sufficiency of supply, (2) ethics, (3) quality and safety, and (4) innovation for non-profit organizations.
Given that legislation and policies impacting tissue and cell donation and transplantation vary significantly across jurisdictions, this field’s issues warrant separate considerations from other challenges affecting OTDT systems. The recommendations are not intended to provide a prescriptive pathway for implementation. Instead, the recommendations provide a general framework for developing a fair, ethical, safe, and accessible system supporting patient outcomes and self-sufficiency.
DOMAIN 7: Research and Innovation in Organ Donation
The Research and Innovation in Organ Donation domain provides expert guidance on developing a high-performing and ethically robust deceased donation research framework. The 16 recommendations cover the areas of (1) patient, family, donor, and public involvement in research; (2) donor, surrogate, and recipient consent within a research ethics framework; and (3) data management.
The recommendations are intended to strengthen a jurisdiction’s OTDT system while building and maintaining public trust. The domain followed the US National Academics of Science, Engineering, and Medicine report’s goals of developing a robust and ethical deceased donation research framework.
ity of Alberta and has received training in patient-oriented research through the University of Calgary’s PACER (Patient and Community Engagement Research) Program. He is the Patient, Family, and Donor Partnerships & Education Manager with the Canadian Donation and Transplantation Research Program. In this role, Manuel builds relationships patient partners with investigators and strengthens capacity among CDTRP patient partners.
Anders Billström 
Gareth Wiltshire
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Sherrie Logan 
born and raised in Edmonton, AB. With a degree in Music Performance (saxophone performance) and Education, Lindsey has taught for over a decade in the Edmonton Public School system. When she is not teaching, she is very involved in the music community, performing in the Edmonton Winds, conducting her own community ensemble (The Beer League Band) and on numerous musical boards across the province. For the past 5 years, Lindsey has had to take a break from teaching after having her amazing son, George. Maternity leave did not goes as expected as George was diagnosed with Dilated Cardiomyopathy at 5 months old and required 2 heart transplants before the age of 4. During this time, Lindsey has also began to dedicate her time building and expanding her charity: Big Gifts for Little Lives, where they raise money to fund Pediatric Heart Transplant research at the Stollery.
Dr. Caigan Du is a scientist at the Vancouver Coastal Health Research Institute and an assistant professor in the Department of Urologic Sciences at the University of British Columbia. He received a Ph.D. degree in Biochemistry in UK and postdoctoral training in Immunology in USA. He is interested in the pathogenesis of kidney ischemia-reperfusion injury and transplant rejection, and molecular control of urinary malignancies. He has been studying the impact of kidney donor-derived factors on renal allograft rejection, and the molecular pathways of kidney injury and regeneration in experimental models. He is also interested in developing medical solution including drugs made from natural compounds for all kinds of health problems, including immune disorders, organ preservation, kidney failure and urinary cancer. He is the PI of many grant supports from the Kidney Foundation of Canada and the Canadian Institutes of Health Research.
Heather Badenoch is a non-directed living liver donor and communications strategist. As the president of Village PR, she provides strategic communications direction and training to not-for-profit clients in community and health. An active transplant volunteer, Heather helps transplant candidates find living donors by running their public appeals, small and large, pro-bono. She also mentors potential living donors on the path to living donation. Heather is a volunteer with the UHN Centre for Living Organ Donation and the Canadian Donation and Transplant Research Program. She and her spouse adopt rescue dogs and volunteer together with Community Veterinary Outreach, a group providing free veterinary care to the pets of people who are homeless.
Sean Dicks is a clinical psychologist who has 20 years’ experience supporting both families of organ donors and transplant recipients. While it is rare for him to have contact with a donor family and recipient linked to the same organ donation-transplantation event, his contact with families who have lived experience with organ donation on the one hand, and patients who have received transplants on the other hand has provided opportunities to explore how their journeys become linked when they attempt to make sense of and find meaning in their respective crises.
Terri Hansen-Gardiner is a Cree speaking Metis woman from Northern Saskatchewan as well as a 10 year Breast Cancer Survivor. Her tireless spirit and dedication to her community is undeniable. Terri is a cancer survivor who travels around the province to provide assistance, information, and support to Indigenous patients who are trying to access and navigate the cancer care system.
Dr. Golnaz Karoubi is Assistant Scientist at the Toronto General HospitalResearch Institute and principal investigator in the Latner Thoracic Research Labs. She currently holds an Assistant Professor appointment in the department of Laboratory Medicine and Pathobiology and a cross-appointment in the department of Mechanical and Industrial Engineering at the University of Toronto. Dr. Karoubi received her PhD in Applied Science and Engineering at the University of Toronto and joined the Lung Regenerative Medicine Program in the Department of Clinical Research in Berne University, Switzerland for a post-doctoral research fellowship. She stayed on as a Group Leader in 2008 to direct the basic and transitional science as related to Cancer Stem Cell and Lung Regenerative Medicine in the Department of Biomedical Research at the University of Berne until 2012. In early 2012, she joined the team of Dr. Tom Waddell at the Toronto General Hospital Research Institute as a Senior Scientific Associate and was appointed to Assistant Scientist at the Toronto General Hospital Research Institute (University Health Network) in November 2019 and to Assistant Professor in the Department of Laboratory Medicine and Pathobiology in July 2020.
Dr. Haykal graduated from the University of Ottawa Faculty of Medicine in2007 as class valedictorian and silver medalist, and subsequently completed her residency training in Plastic and Reconstructive Surgery at the University of Toronto in 2016. During her residency, she completed a four-year Doctorate of Philosophy (PhD) in tissue engineering, regenerative medicine and immunology with a focus on tracheal reconstruction. She obtained numerous grants and awards including a CIHR Vanier Scholarship. Dr. Haykal then pursued fellowship training in microsurgical reconstruction at the Albany Medical Centre in New York. Dr. Haykal joined the University Health Network and the Toronto General Hospital in 2018. Her clinical focus is on complex oncological reconstruction and microsurgical reconstruction of the breast, head and neck and extremity. She started a lymphedema program in 2019 where she offers microsurgical techniques for the treatment of lymphedema.
Dr. Ahmed is a Professor in the Cumming School of Medicine at the University of Calgary. The recipient of the 2022 Hypertension Canada Senior Investigator Award, she is a nephrologist and clinician-scientist with a focus on sex and gender differences in human cardiovascular/kidney physiology and clinical outcomes. Dr. Ahmed is the Vice Chair (Research) for the Department of Medicine, Lead of the Libin Institute Women’s Cardiovascular Health Research Initiative at the University of Calgary and Lead of the Alberta Strategy for Patient Oriented Research Capacity Development Platform. Dr. Ahmed is an Advisory Board member for the Canadian Institutes of Health Research Institute of Gender and Health, a member of the Canadian Medical Association Journal Governing Council and the President-Elect for the Organization for the Study of Sex Differences.
r. Christopher Nguan is an Associate Professor at the University of British Columbia in the Department of Urological Sciences, Surgical Head of Kidney Transplantation at Vancouver General Hospital and the Director of the Surgical Technologies Experimental Laboratory & Advanced Robotics (STELLAR) facility at Vancouver General Hospital.
r Caroline Lamarche is a clinician scientist and transplant nephrologist at Maisonneuve-Rosemont Hospital. She is an assistant clinical professor at the Université de Montréal. After her nephrology training at the Université de Montréal (2015), she completed a Master degree on the use of adoptive immunotherapy to treat/prevent BK nephropathy in kidney transplant recipients. She then pursued a post-doctoral fellowship with Dr. Megan Levings at the University of British Columbia on the use of chimeric antigen receptor (CAR) regulatory T cells (Tregs) to induce transplant tolerance. Her lab is working on the development of adoptive immunotherapy in nephrology and understanding Treg dysfunction.
Dr. Tandon is an Associate Professor of Medicine, Co-Director of the Cirrhosis Care Clinic, Transplant Hepatologist and lead of the Cirrhosis Care Alberta quality improvement program. She obtained her training at the University of Alberta, the Hospital Clinic in Barcelona and Yale University. Her clinical practice and research are focused on cirrhosis with research interests including cirrhosis related complications, malnutrition, frailty, exercise therapy, palliative care, integrative health approaches such as meditation and knowledge translation. It is her career goal to provide wholistic, interdisciplinary, evidence based, patient-centered care through education, empowerment, engagement and team-work.
Emily is a PhD student at the University of Alberta, where she completed her Master of Science (MSc) degree in medicine. With a passion for patient-oriented research and a commitment to improving health outcomes, Emily’s doctoral project focuses on EMPOWER, a 12-week online mind-body wellness program designed for adults living with chronic health conditions.
Dr Basil S. Nasir, M.B.B.Ch
Dr. Victor Ferreira is an Assistant Scientist in the Ajmera Transplant Centre at the University Health Network (UHN) and the Toronto General Hospital Research Institute (TGHRI). He is also an Assistant Professor at the University of Toronto in the Department of Laboratory Medicine and Pathobiology (LMP). He completed his PhD in Medical Sciences – Infection and Immunity Specialization at McMaster University in 2014 and post-doctoral training at UHN. His research program is focused on three pillars: I) using systems vaccinology to reveal insights into vaccine responses in immunocompromised individuals like transplant recipients; II) characterizing the impact of chronic viral infection on host immune responses; and III) developing novel methods for eliminating latent viruses in human organs. His work has been cited >2,500 times and is published in journals including the New England Journal of Medicine, Nature Immunology, the Lancet Infectious Diseases, Clinical Infectious Diseases, the American Journal of Transplantation and Journal of Infectious Diseases.
Chemical Engineering as an Assistant Professor in August 2014. She is a biochemical engineer with expertise in bioprocess development, high‑throughput screening and stem cell culture optimization. Her research aims to develop bioprocesses to produce and transplant therapeutic cells to treat diabetes and cardiovascular disease. She notably developed new methods to encapsulate pancreatic islets, as well as vascular biomaterials surface modification strategies which are now applied by other researchers around the world. Her emerging leadership in bioengineering was recognized through the 2014 Martin Sinacore Outstanding Young Investigator Award from Engineering Conferences International & Biogen Idec, as well as the “Étoiles effervescence” award from Montreal InVivo.
