{"id":21713,"date":"2023-02-07T08:26:49","date_gmt":"2023-02-07T13:26:49","guid":{"rendered":"https:\/\/cdtrp.ca\/?p=21713"},"modified":"2023-04-05T07:49:48","modified_gmt":"2023-04-05T12:49:48","slug":"connecte-a-la-recherche-liu","status":"publish","type":"post","link":"https:\/\/cdtrp.ca\/fr\/connecte-a-la-recherche-liu\/","title":{"rendered":"S\u00e9rie Connect\u00e9 \u00e0 la recherche &#8211; Dr Mingyao Liu"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-dropshadow imageframe-1 hover-type-none\" style=\"-webkit-box-shadow: 3px 3px 7px rgba(0,0,0,0.3);box-shadow: 3px 3px 7px rgba(0,0,0,0.3);\"><img decoding=\"async\" width=\"1024\" height=\"576\" title=\"Feb 21 &#8211; Liu_FR\" src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR.png\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR-1024x576.png\" alt class=\"lazyload img-responsive wp-image-21589\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271600%27%20height%3D%27900%27%20viewBox%3D%270%200%201600%20900%27%3E%3Crect%20width%3D%271600%27%20height%3D%27900%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR-200x113.png 200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR-400x225.png 400w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR-600x338.png 600w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR-800x450.png 800w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR-1200x675.png 1200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/01\/Feb-21-Liu_FR.png 1600w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 1200px\" \/><\/span><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><\/div><div class=\"fusion-text fusion-text-1\"><h4 class=\"p2 fusion-responsive-typography-calculated\" data-fontsize=\"24\" data-lineheight=\"36px\"><strong>S\u00e9rie Connect\u00e9 \u00e0 la recherche<\/strong><\/h4>\n<p>Le PRDTC est heureux de tenir sa nouvelle s\u00e9rie de pr\u00e9sentations bas\u00e9es sur la discussion intitul\u00e9e \u00ab <strong>Connect\u00e9 \u00e0 la recherche<\/strong>. \u00bb<\/p>\n<p>Cette s\u00e9rie rassemble en une seule entit\u00e9 les r\u00e9unions des th\u00e8mes et des groupes de travail qui visaient \u00e0 partager et \u00e0 discuter des derniers r\u00e9sultats de recherche \u00e0 travers le r\u00e9seau, avec notre s\u00e9rie de webinaires, qui mettaient en vedette des conf\u00e9renciers nationaux et internationaux. Les r\u00e9unions des th\u00e8mes de recherche et les groupes de travail visant \u00e0 \u00e9laborer de nouvelles initiatives, de nouveaux projets ou de nouvelles subventions seront programm\u00e9es s\u00e9par\u00e9ment, environ trois fois par an et par groupe.<\/p>\n<p><strong>La nouvelle s\u00e9rie de pr\u00e9sentations se d\u00e9roulera toutes les deux semaines, le mardi, de 13h \u00e0 14h HE.<\/strong><\/p>\n<p>Notre objectif est de permettre \u00e0 nos membres de conna\u00eetre et d\u2019assister facilement \u00e0 des pr\u00e9sentations de haute qualit\u00e9 dans tous les th\u00e8mes et sujets d\u2019int\u00e9r\u00eat. Nous souhaitons que les chercheurs, les stagiaires et les patients, familles et donneurs partenaires participent activement aux discussions, comme s\u2019il s\u2019agissait d\u2019un d\u00eener en famille plut\u00f4t que d\u2019une pr\u00e9sentation formelle.<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:10px;margin-bottom:10px;width:100%;\"><\/div><div style=\"text-align:center;\"><a class=\"fusion-button button-flat fusion-button-default-size button-custom fusion-button-default button-1 fusion-button-default-span fusion-button-default-type\" style=\"--button_accent_color:#ffffff;--button_border_color:#ffffff;--button_accent_hover_color:#edf2f7;--button_border_hover_color:#ffffff;--button_gradient_top_color:#aa0e13;--button_gradient_bottom_color:#aa0e13;--button_gradient_top_color_hover:#aa0e13;--button_gradient_bottom_color_hover:#aa0e13;--button_text_transform:uppercase;\" target=\"_self\" href=\"https:\/\/cdtrp.ca\/fr\/publications\/serie-de-webinaires-2023\/\"><i class=\"fa-laptop-code fas button-icon-left\" aria-hidden=\"true\"><\/i><span class=\"fusion-button-text\">Visitez le site web<\/span><\/a><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-parallax-none nonhundred-percent-fullwidth non-hundred-percent-height-scrolling lazyload\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-background-size:cover;--awb-flex-wrap:wrap;\" data-bg=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2022\/12\/CDTRP-2023-Webinar-Series.png\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"--awb-bg-size:cover;--awb-margin-top:50px;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-2\"><h5><strong>Dr Mingyao Liu : <em>Molecular mechanisms and therapeutic targets of human lung transplant injury\u00a0<\/em><\/strong><\/h5>\n<p>Le 21 f\u00e9vrier dernier, nous avons eu le plaisir d\u2019accueillir <b>Dr Mingyao Liu<\/b> pour une pr\u00e9sentation intitul\u00e9e : <em>Molecular mechanisms and therapeutic targets of human lung transplant injury<\/em>, dans le cadre du Th\u00e8me 3 du PRDTC &#8211; Des greffons de qualit\u00e9 optimale.<\/p>\n<\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;\"><\/div><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-text fusion-text-3\"><h5><strong>Description<\/strong><\/h5>\n<p>La conservation au froid et la reperfusion \u00e0 chaud sont des \u00e9tapes in\u00e9vitables de la transplantation d&rsquo;organes. Ces changements spectaculaires soumettent les greffons \u00e0 des contraintes suppl\u00e9mentaires et provoquent des l\u00e9sions d&rsquo;isch\u00e9mie-reperfusion qui entra\u00eenent un dysfonctionnement primaire du greffon. Pour \u00e9tudier les m\u00e9canismes sous-jacents, les mod\u00e8les animaux et les observations cliniques sont les principaux outils. Au cours des vingt derni\u00e8res ann\u00e9es, nous avons d\u00e9velopp\u00e9 une banque de tissus pour collecter des \u00e9chantillons de tissus pulmonaires, de perfusat EVLP, de plasma de patients et de liquide de lavage broncho-alv\u00e9olaire. R\u00e9cemment, nous avons utilis\u00e9 ces \u00e9chantillons pour \u00e9tudier l&rsquo;expression des g\u00e8nes (transcriptomique), des prot\u00e9ines (prot\u00e9omique) et des m\u00e9tabolites (m\u00e9tabolomique). L&rsquo;omique permet d&rsquo;\u00e9tudier toutes les mol\u00e9cules cibl\u00e9es en m\u00eame temps, afin de d\u00e9couvrir les voies et les m\u00e9canismes sous-jacents. Ces \u00e9tudes ont r\u00e9v\u00e9l\u00e9 des m\u00e9canismes importants qui peuvent \u00eatre utilis\u00e9s comme cibles pour d\u00e9velopper de nouvelles th\u00e9rapies.<\/p>\n<\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:10px;margin-bottom:10px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-video fusion-youtube fusion-aligncenter\" style=\"--awb-max-width:900px;--awb-max-height:506px;--awb-width:100%;\"><div class=\"video-shortcode\"><div class=\"fluid-width-video-wrapper\" style=\"padding-top:56.22%;\" ><iframe title=\"YouTube video player 1\" src=\"https:\/\/www.youtube.com\/embed\/TbhcYL-LSuU?wmode=transparent&autoplay=0\" width=\"900\" height=\"506\" allowfullscreen allow=\"autoplay; fullscreen\"><\/iframe><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-flex-align-self-center\" style=\"--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:2.88%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-text fusion-text-4\"><h5><strong>\u00c0 propos du Dr Mingyao Liu<\/strong><\/h5>\n<p>Le Dr Liu est scientifique principal et chef du groupe de recherche sur les soins respiratoires et critiques \u00e0 l&rsquo;Institut de recherche de l&rsquo;H\u00f4pital g\u00e9n\u00e9ral de Toronto, University Health Network. Le Dr Liu est titulaire de la chaire James et Mary Davie: Lung Injury, Repair and Regeneration. Le Dr Liu est directeur de l&rsquo;Institute of Medical Science et professeur de chirurgie, de m\u00e9decine et de physiologie \u00e0 la facult\u00e9 de m\u00e9decine Temerty de l&rsquo;Universit\u00e9 de Toronto.<\/p>\n<p>Le Dr Liu a consacr\u00e9 ses recherches aux l\u00e9sions pulmonaires aigu\u00ebs et \u00e0 la transplantation pulmonaire. En tant que cofondateur des Latner Labs, le Dr Liu s&rsquo;est associ\u00e9 \u00e0 son coll\u00e8gue, le Dr Shaf Keshavjee, pour d\u00e9velopper des objectifs ambitieux de recherche sur la transplantation pulmonaire. Actuellement, il se concentre sur les m\u00e9canismes cellulaires et mol\u00e9culaires des l\u00e9sions d&rsquo;isch\u00e9mie-reperfusion dans les transplantations pulmonaires, et sur le d\u00e9veloppement de nouvelles solutions de pr\u00e9servation des poumons, de perfusats EVLP et de techniques.<\/p>\n<p>Il a re\u00e7u un certain nombre de prix de recherche, dont la m\u00e9daille du jubil\u00e9 de diamant de la reine Elizabeth II.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-center\" style=\"--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-dropshadow imageframe-2 hover-type-none\" style=\"-webkit-box-shadow: 3px 3px 7px rgba(0,0,0,0.3);box-shadow: 3px 3px 7px rgba(0,0,0,0.3);\"><img decoding=\"async\" width=\"2268\" height=\"2560\" title=\"T4MXQF_Liu_Mingyao\" src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-scaled.jpg\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-scaled.jpg\" alt class=\"lazyload img-responsive wp-image-21717\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272268%27%20height%3D%272560%27%20viewBox%3D%270%200%202268%202560%27%3E%3Crect%20width%3D%272268%27%20height%3D%272560%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-200x226.jpg 200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-400x451.jpg 400w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-600x677.jpg 600w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-800x903.jpg 800w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-1200x1354.jpg 1200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/02\/T4MXQF_Liu_Mingyao-scaled.jpg 2268w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px\" \/><\/span><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":21725,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[81,37,91],"tags":[],"class_list":["post-21713","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-en-vedette","category-non-classifiee","category-webinaires-anterieurs"],"_links":{"self":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts\/21713"}],"collection":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/comments?post=21713"}],"version-history":[{"count":11,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts\/21713\/revisions"}],"predecessor-version":[{"id":22747,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts\/21713\/revisions\/22747"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/media\/21725"}],"wp:attachment":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/media?parent=21713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/categories?post=21713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/tags?post=21713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}