{"id":12170,"date":"2021-08-03T09:59:40","date_gmt":"2021-08-03T14:59:40","guid":{"rendered":"https:\/\/cdtrp.ca\/?p=12170"},"modified":"2023-07-04T08:53:43","modified_gmt":"2023-07-04T13:53:43","slug":"recipiendaire-de-la-bourse-cdtrp-research-innovation-corinne-hoesli-et-steven-paraskevas","status":"publish","type":"post","link":"https:\/\/cdtrp.ca\/fr\/recipiendaire-de-la-bourse-cdtrp-research-innovation-corinne-hoesli-et-steven-paraskevas\/","title":{"rendered":"R\u00e9cipiendaire de la bourse CDTRP Research Innovation &#8211;  Making every pancreatic islet count \u2013 engineering a vascularized transplantation system to treat type 1 diabetes (Corinne Hoesli et Steven Paraskevas)"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-dropshadow imageframe-1 hover-type-none\" style=\"-webkit-box-shadow: 3px 3px 7px rgba(0,0,0,0.3);box-shadow: 3px 3px 7px rgba(0,0,0,0.3);\"><img decoding=\"async\" width=\"1024\" height=\"576\" title=\"CDTRP Innovation grant 2021_Hoesli_Paraskevas\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272240%27%20height%3D%271260%27%20viewBox%3D%270%200%202240%201260%27%3E%3Crect%20width%3D%272240%27%20height%3D%271260%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2021\/08\/CDTRP-Innovation-grant-2021_Hoesli_Paraskevas_FR.png\" alt class=\"lazyload img-responsive wp-image-12172\"\/><\/span><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-1\"><h4>R\u00e9cipiendaire de la bourse CDTRP Research Innovation &#8211; Making every pancreatic islet count \u2013 engineering a vascularized transplantation system to treat type 1 diabetes (Corinne Hoesli et Steven Paraskevas)<\/h4>\n<p data-pm-slice=\"1 1 &#091;&#093;\">Gr\u00e2ce \u00e0 sa collaboration avec des organisations partenaires, le PRDTC est heureux d&rsquo;offrir son <a href=\"https:\/\/cdtrp.ca\/fr\/support-a-la-recherche\/concours-de-subventions-a-la-recherche-et-linnovation-du-prdtc\/\">Concours de subventions \u00e0 la recherche et l\u2019innovation<\/a> pour financer de nouvelles id\u00e9es de projets passionnants. Au cours des prochaines semaines, nous pr\u00e9senterons tous les projets financ\u00e9s dans le cadre du concours de 2021.<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-double sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;border-bottom-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-2\"><h4 data-pm-slice=\"1 1 &#091;&#093;\">Porjet financ\u00e9 gr\u00e2ce \u00e0 <strong>CDTRP Research Innovation Grant<\/strong><\/h4>\n<p><strong>Titre : <em>Making every pancreatic islet count \u2013 engineering a vascularized transplantation system to treat type 1 diabetes<\/em><\/strong><\/p>\n<ul>\n<li>Chercheurs principaux : Corinne Hoesli et Steven Paraskevas<\/li>\n<li>Principale affiliation : Universit\u00e9 McGill<\/li>\n<li>Th\u00e8me 3<\/li>\n<\/ul>\n<h5>R\u00e9sum\u00e9 (en anglais)<\/h5>\n<p data-pm-slice=\"1 1 &#091;&#093;\"><em>Type 1 diabetes (T1D) is an autoimmune disorder caused by the destruction of the insulin-producing beta cells of the pancreas. Insulin regulates blood glucose levels. Even with regular blood glucose monitoring and insulin administration, people with T1D experience significant challenges controlling blood glucose. Low blood glucose levels can lead to loss of conscience and even death, while high blood glucose levels are associated with long-term complications such as heart disease, loss of feeling in extremities and loss of vision. Instead of replacing the insulin hormone, the insulin-producing beta cells can be replaced through a procedure termed islet transplantation. Islet transplantation can avoid the need for insulin in 70% of recipients for at least 2 years and reduces the risks of hypoglycemia for several years. Unfortunately, this therapy is not accessible to most people with T1D due to limited cell supply from organ donors. Moreover, islet transplant recipients must take immune suppressive drugs for the rest of their lives after the procedure, increasing risks of infection and cancer. The objective of this project is to design a transplantation device that could be combined with a variety of islet cell sources, increasing access to the therapy. This islet encapsulation device would also protect the graft from the immune system, avoiding the need for immune suppression. Finally, the device would be retrievable if complications arise. While other encapsulation devices are being developed, a unique feature of our new device is the optimization of graft survival via short and long-term islet oxygenation.<\/em><\/p>\n<p data-pm-slice=\"1 1 &#091;&#093;\"><strong> Vous souhaitez en savoir plus ? Ce projet sera pr\u00e9sent\u00e9 \u00e0 la r\u00e9union du Th\u00e8me 3 le 18 ao\u00fbt (<a href=\"https:\/\/cdtrp.ca\/fr\/theme-3-agenda-de-la-reunion-du-18-aout\/\">plus de d\u00e9tails ici<\/a>).<\/strong><\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-double sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;border-bottom-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-3\"><p style=\"text-align: center;\"><a href=\"https:\/\/cdtrp.ca\/fr\/resultats-du-concours-2021-de-subventions-a-la-recherche-et-linnovation-du-prdtc-11-nouveaux-projets-finances\/\">Consultez les r\u00e9sultats du Concours 2021 de subventions \u00e0 la recherche et l\u2019innovation du PRDTC<\/a>.<\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/cdtrp.ca\/fr\/concours-innovation-prdtc-laureats\/\">Consultez les anciens laur\u00e9ats du Concours de subventions \u00e0 la recherche et l\u2019innovation du PRDTC.<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":12185,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[81,37],"tags":[],"class_list":["post-12170","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-en-vedette","category-non-classifiee"],"_links":{"self":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts\/12170"}],"collection":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/comments?post=12170"}],"version-history":[{"count":6,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts\/12170\/revisions"}],"predecessor-version":[{"id":24758,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/posts\/12170\/revisions\/24758"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/media\/12185"}],"wp:attachment":[{"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/media?parent=12170"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/categories?post=12170"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdtrp.ca\/fr\/wp-json\/wp\/v2\/tags?post=12170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}