{"id":20213,"date":"2022-10-26T10:52:38","date_gmt":"2022-10-26T15:52:38","guid":{"rendered":"https:\/\/cdtrp.ca\/en\/?post_type=spucpt&p=20213"},"modified":"2022-10-26T10:57:22","modified_gmt":"2022-10-26T15:57:22","slug":"amal-trigui-3mt","status":"publish","type":"spucpt","link":"https:\/\/cdtrp.ca\/en\/spucpt\/amal-trigui-3mt\/","title":{"rendered":"Amal Trigui 3MT"},"content":{"rendered":"

Amal Trigui’s bio<\/strong><\/p>\n

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Amal Trigui obtained her bachelor\u2019s degree in medical biology in 2014 from\u00a0the University of Sfax in Tunisia. In 2019, she obtained her master’s degree in research in health sciences from the Universit\u00e9 de Sherbrooke. She is currently a doctoral student in nutrition at the Faculty of Medicine of the Universit\u00e9 de Montr\u00e9al. Her research project is taking place in the CHUM research center (CRCHUM), particularly in the Hepato-neuro laboratory where she is interested in malnutrition and sarcopenia before and after liver transplantation<\/p>\n

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Longitudinal evolution of nutritional risk and muscle function of patients waiting for liver transplantation and the effect of early nutritional intervention following the transplantation<\/strong><\/p>\n

Aisha Adil, Golnaz Karoubi, Siba Haykal<\/em><\/p>\n

In patients living with cirrhosis and waiting for liver transplantation (LT), protein-energy malnutrition is the most common complication (&gt; 80%). After LT, nutritional status can worsen rapidly leading to sarcopenia (loss of muscle mass and function).<\/p>\n

Objectives: 1) Assess longitudinal changes in nutritional risk, muscle function and quality of life in cirrhotic patients awaiting LT. 2) Evaluate the effect of early nutritional supplementation rich in protein, beta-hydroxy-beta-methylbutyrate (HMB) and energy, after LT, on muscle mass and function, nutritional risk and quality of life.<\/p>\n

Method: A randomized controlled pilot study is conducted including 30 patients going through LT. Muscle mass (CT scan), muscle function (chair stand test), nutritional risk (liver disease undernutrition screening tool) and quality of life (SF-36) are assessed every 3 months before LT, immediately after discharge from hospital and 12 weeks post-LT. At LT, participants are randomized in: (1) intervention group (n=15) receiving standard nutritional care as well as supplements rich in protein, HMB and energy for 12 weeks and (2) control group (n=15) receiving standard nutritional care.
\nResults: Currently, 26 patients awaiting LT are included. One participant was transplanted. The mean age is 51.3 \u00b1 12.9 years. The most common etiology is alcohol (33 %). 84 % of patients are at risk of malnutrition which remain unchanged within up to one year on the waitlist. Muscle function is impaired (18.1 \u00b1 11.0 s vs. 12.6 s in healthy patients; p &lt; 0,001) and decreased with time on waitlist. Regarding quality of life, the score of physical heath (41.8% \u00b1 18.6) and mental health (52.1% \u00b1 25) are below normal. The quality of life tended to decrease over time before LT.<\/p>\n

Conclusion: The majority of patients waiting for a LT are at risk of malnutrition, display altered muscle function, and a tendency of decreased quality of life. These preliminary data support the need for early nutritional support after LT.<\/p>\n","protected":false},"author":6,"template":"","class_list":["post-20213","spucpt","type-spucpt","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/spucpt\/20213"}],"collection":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/spucpt"}],"about":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/types\/spucpt"}],"author":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/users\/6"}],"wp:attachment":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/media?parent=20213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}