{"id":3331,"date":"2020-03-05T16:51:02","date_gmt":"2020-03-05T16:51:02","guid":{"rendered":"https:\/\/cdtrp.ca\/?p=3331"},"modified":"2020-03-05T19:11:47","modified_gmt":"2020-03-05T19:11:47","slug":"2020-a-year-for-canada-to-leap-ahead-in-donation-and-transplantation-research","status":"publish","type":"post","link":"https:\/\/cdtrp.ca\/en\/2020-a-year-for-canada-to-leap-ahead-in-donation-and-transplantation-research\/","title":{"rendered":"2020: A year for Canada to leap ahead in donation and transplantation research"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"--awb-bg-size:cover;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-1 fusion-no-medium-visibility\" id=\"Scientific-Directors\"><div class=\"span5 the-side-caption\">\n<div style=\"text-align: left;\">\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"lazyload alignnone size-full wp-image-3316\" src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-10.09.48-AM.png\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-10.09.48-AM.png\" alt=\"\" width=\"552\" height=\"192\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27552%27%20height%3D%27192%27%20viewBox%3D%270%200%20552%20192%27%3E%3Crect%20width%3D%27552%27%20height%3D%27192%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-10.09.48-AM-200x70.png 200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-10.09.48-AM-300x104.png 300w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-10.09.48-AM-400x139.png 400w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-10.09.48-AM.png 552w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 552px) 100vw, 552px\" \/><\/p>\n<p>2020 is a year of opportunity for our network. Many of you will remember our roots, as we together founded the Canadian National Transplantation Research Program in 2013. The goal was to bring together our country&#8217;s diverse donation and transplantation research communities, an ongoing effort that we are just as passionate about today. Over the last 6 years, our network has grown to include more than 300 scientists, students, collaborators, patient\/family\/donor partners and knowledge users at 33 sites across Canada, working together on our shared goals through research, innovation, and knowledge translation projects.<\/p>\n<p>In 2018, we refreshed the vision of our network and articulated the next steps towards our mission of achieving <em>One-Transplant-for-Life<\/em>: that Canada fulfills every donation opportunity and realizes the potential of transplantation as a true, cost-effective and final cure for many chronic diseases and refractory blood cancers. We also renamed the network the <em>Canadian Donation and Transplantation Research Program<\/em>, recognizing the importance and equal weight of the donation communities with the transplant communities, together with patients, families and donors. With a redesigned structure, we are now offering enhanced research support and infrastructure to the community, to help accelerate research and innovation projects, leverage the vast interdisciplinary expertise of the network, grow funding opportunities and success rates for our members, and position our trainees and early career researchers for successful careers in the field. We encourage all of you to explore the many <a href=\"https:\/\/cdtrp.ca\/en\/platforms\/data-innovations\/\">resources available<\/a> and reach out to <a href=\"https:\/\/cdtrp.ca\/en\/contact-us\/\">network staff<\/a> for more information.<\/p>\n<p>With our members\u2019 and partners\u2019 collective and coordinated efforts, we are moving the field forward in an array of new and exciting ways. Here are just a few highlights of work going on across the network:<\/p>\n<ul>\n<li>Theme 1 (Create a culture of donation) will be hosting a conference call on March 18, 2020 to review the new amendment to the Medical Assistance in Dying bill. The review will be led by Jennifer Chandler, with contributions from Matthew Weiss and perspectives from Laurie Blackstock, Theme 1 patient, family, donor lead. For more information and to join the call, contact us at <a href=\"mailto:info@cdtrp.ca\">info@cdtrp.ca<\/a>.<\/li>\n<li>Members of Theme 2 (Inform universal practices for donation) recently met with Dr. Caroline Tait and others to better understand the M\u00e9tis, Inuit and First Nations perspective on the differences of neurological and circulatory death and how that can better inform practices for donation nationwide.<\/li>\n<li>Members of Theme 3 (Engineer and allocate better grafts) were recently awarded CIHR funding to study a novel cell death pathway and its role in long-term graft survival. Inhibiting this pathway could be a strategy to prevent cell death, organ injury and thus transplant rejection, as well as increasing the possibility for donation after circulatory determined death.<\/li>\n<li>Members of Theme 4 (Tailor an optimized immune system for each patient) are trialling photopheresis-based cell therapy for the treatment of chronic graft vs host disease in a national multi-center clinical trial (CARE). Patient recruitment and sample collection are now complete, and the analysis phases, involving collaborations across the network, are underway.<\/li>\n<li>Members of Theme 5 (Restore long-term health) are working with patients and families to implement tools to capture patient-reported outcomes in solid-organ transplant recipients. The overarching objective is to improve health outcomes by implementing ePROMs into standard clinical practice.<\/li>\n<\/ul>\n<p>CIHR has been an outstanding supporter of our vision for donation and transplantation research in Canada since our inception. Now in 2020, it is time for our maturing network to work toward become self-sustaining, and find new ways to continue developing the resources and supports that can help bring our communities together and increase the quality of our research and training. We are looking forward to further strengthening the relationships among members and with our partners to achieve this goal. Over the course of the year, we will be evaluating the CDTRP\u2019s progress, assessing what activities and supports are offering the most value to the community, and considering what may need recalibration. You may be contacted in the coming months for your thoughts, and we look forward to engaging with you in these ongoing conversations. As always, we are grateful for all of our members\u2019 and partners\u2019 perspectives and contributions as we work toward our shared goal of enhancing collaboration, supporting high quality training, advancing the quality of donation and transplantation research, and transforming research into an improved quality of life for Canadians.<\/p>\n<p>Lori West, Scientific Director<\/p>\n<p>Marie-Jos\u00e9e H\u00e9bert, Scientific Co-Director<\/p>\n<p>Sonny Dhanani, Associate Director<\/p>\n<p>Jean-S\u00e9bastien Delisle, Associate Director<\/p>\n<\/div>\n<\/div>\n<div class=\"span7\">\n<div class=\"carousel-image-container\" style=\"text-align: left;\"><\/div>\n<\/div>\n<\/div><div class=\"fusion-text fusion-text-2 fusion-no-medium-visibility\" id=\"Executive-Director\"><div class=\"span5 the-side-caption\">\n<div style=\"text-align: left;\">\n<p><img decoding=\"async\" class=\"lazyload alignnone size-full wp-image-3306 aligncenter\" src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-9.29.44-AM.png\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-9.29.44-AM.png\" alt=\"\" width=\"562\" height=\"144\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27562%27%20height%3D%27144%27%20viewBox%3D%270%200%20562%20144%27%3E%3Crect%20width%3D%27562%27%20height%3D%27144%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-9.29.44-AM-200x51.png 200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-9.29.44-AM-300x77.png 300w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-9.29.44-AM-400x102.png 400w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-05-at-9.29.44-AM.png 562w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 562px) 100vw, 562px\" \/><\/p>\n<\/div>\n<\/div>\n<div class=\"span7\">\n<div class=\"carousel-image-container\" style=\"text-align: left;\">\n<p>In pursuit of our revised, bold vision to achieve the <strong>One-Transplant-for-Life Challenge<\/strong> by fulfilling every donation opportunity and turning transplantation into a cure, the CDTRP recently restructured the research supported within the network into 5 inter-related and comprehensive <a href=\"https:\/\/cdtrp.ca\/en\/research\/\">Themes.<\/a>\u00a0 Over the past two years, the CDTRP has successfully transitioned from a national network that funds a selected group of research projects to a national structure that supports, enables and fosters the development, execution, implementation and translation of new research ideas and collaborations. In support of our <a href=\"https:\/\/cdtrp.ca\/en\/get-involved\/\">growing community,<\/a> we are fostering collaborations across disciplines, including basic science, clinical research, engineering, chemistry, law, ethics, economics, social sciences and machine learning, amongst others.<\/p>\n<p>As the new Executive Director, I am committed to ensuring that the support that we provide to the Donation and Transplantation research community is in line with our <a href=\"https:\/\/cdtrp.ca\/en\/about\/\">One-Transplant-for-Life mission<\/a>. I am also convinced that our revised CDTRP framework provides essential <a href=\"https:\/\/cdtrp.ca\/en\/platforms\/data-innovations\/\">infrastructure elements<\/a> to help our community work with partners and stakeholders to increase their competitiveness and launch innovative and collaborative projects. I am very proud that CDTRP now represents the \u2018go to\u2019 platform in Canada, where investigators bring new ideas, find collaborators and patient\/family\/donor partners, make connections to other disciplines and receive individualized resources and infrastructure support to strengthen their research and increase success. At the heart of our work, I would like to underline the dedication, support and ongoing commitment of our <a href=\"https:\/\/cdtrp.ca\/en\/about\/#founding-partners\">partners and founders<\/a> including CIHR, all of Canada\u2019s large donation and transplantation charities, the federal and provincial governments, start-ups, members of the pharma and technology industry and a growing number of international collaborators.<\/p>\n<p>I am truly honoured to lead an extraordinary team in which each staff member brings dedication and passion to their work. \u00a0Our fresh <a href=\"http:\/\/cdtrp.ca\">new website<\/a> reflects our ongoing commitment to be an innovative, dynamic force in supporting the research to achieve the <strong>One-Transplant-for-Life Challenge. <\/strong>We look forward to the future, and are excited for the development and growth of numerous collaborative initiatives and <a href=\"https:\/\/cdtrp.ca\/en\/events\/\">events<\/a> throughout 2020!<\/p>\n<p>M\u00e9lanie Dieud\u00e9, Ph.D.<\/p>\n<p>Executive Director<\/p>\n<\/div>\n<\/div>\n<\/div><div class=\"fusion-text fusion-text-3 fusion-no-medium-visibility\"><p><img decoding=\"async\" class=\"lazyload wp-image-3294 aligncenter\" src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526.jpg\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526.jpg\" alt=\"\" width=\"370\" height=\"271\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27370%27%20height%3D%27271%27%20viewBox%3D%270%200%20370%20271%27%3E%3Crect%20width%3D%27370%27%20height%3D%27271%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-200x147.jpg 200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-300x220.jpg 300w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-400x294.jpg 400w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-600x441.jpg 600w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-768x564.jpg 768w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-800x587.jpg 800w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-1024x752.jpg 1024w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-1200x881.jpg 1200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526-1536x1128.jpg 1536w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/03\/girl-leaping-scaled-e1583420095526.jpg 1708w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 370px) 100vw, 370px\" \/><\/p>\n<h4>Coming in 2020<\/h4>\n<h5 style=\"text-align: left;\">Save the date! The CDTRP Annual Meeting will be held Dec 2-4, 2020 in Kelowna, BC.<\/h5>\n<h5>Upcoming webinars\/training events<\/h5>\n<p>The 2019-2020 Webinar Series devoted to Cross Cutting Priorities in Donation and Transplantation Research is well underway! Two priorities have already been covered: (1) Sex and Gender and (2) Pediatric, Adolescent and Elderly Populations. Each priority topic includes multiple webinars. If you missed any since October 2019, see our <a href=\"https:\/\/www.youtube.com\/channel\/UC6lFeiSGN0lih7r2MJLI42Q\/featured\">YouTube page<\/a>.<\/p>\n<p>Our current featured research priority is Indigenous, Rural and Remote Populations. The first session in this series was entitled \u201cSaskatchewan First Nations and M\u00e9tis Organ Donation and Transplantation Think Tank: Lessons Learned\u201d, presented by Dr. Caroline Tait, and is available <a href=\"https:\/\/cdtrp.ca\/en\/category\/webinars\/cross-cutting-priorities-in-research\/\">here.<\/a><\/p>\n<p>The next webinar to mark on your calendar is:<\/p>\n<p>March 9, 4pm EST \u2013 Dr. Karen Yeates<\/p>\n<p>&#8220;Setting urgent health research priorities for Indigenous, rural and remote populations in Canada: Can we find a balance between the perspectives and needs of communities with those of health researchers?&#8221;<\/p>\n<p>Link to join (open access): <a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fcdtrp.zoom.us%2Fj%2F511879620\">https:\/\/cdtrp.zoom.us\/j\/511879620<\/a><\/p>\n<\/div><div class=\"fusion-text fusion-text-4 fusion-no-medium-visibility\" id=\"Research-Support\"><h4>Research support available from the CDTRP<\/h4>\n<h5>CDTRP Research Innovation Grant update<\/h5>\n<p>The 6<sup>th<\/sup> CDTRP Research Innovation Grant competition is now closed! We received 47 applications this year, which will now undergo competitive peer review. Thank you to all our applicants. We are excited to see our community\u2019s innovative new ideas that will help move Canada toward the <em>One-Transplant-for-Life<\/em> vision.<\/p>\n<p>We are proud to partner with the following organizations to make this year\u2019s competition possible:<\/p>\n<ul>\n<li>Addison Fund \/ Transplant Research Foundation of British Columbia<\/li>\n<li>Alberta Transplant Institute<\/li>\n<li>The Ashley\u2019s Angels Fund<\/li>\n<li>Canadian Liver Foundation<\/li>\n<li>Cystic Fibrosis Canada<\/li>\n<li>Kidney Foundation of Canada<\/li>\n<li>Paladin Labs Inc.<\/li>\n<li>SickKids Transplant &amp; Regenerative Medicine Centre<\/li>\n<li>Universit\u00e9 de Montr\u00e9al<\/li>\n<li>University Health Network Multi-Organ Transplant Program<\/li>\n<\/ul>\n<p>With the generous support of our partners, we are expecting to fund 17 grants of $30,000. Announcements are expected May 7, 2020.<\/p>\n<h5>Support available for upcoming funding applications<\/h5>\n<p>As you prepare your upcoming grant applications, remember that the CDTRP can offer both in-kind and cash resources via a support letter to help strengthen your application and increase your chance of success.\u00a0 Additionally, the network is always happy to help connect you to experts to review and provide feedback on your grant application prior to the deadline. We would be delighted to work with you to build the most competitive applications possible!<\/p>\n<p>CDTRP resources available include:<\/p>\n<ul>\n<li>Economic, Legal, Ethics and Social analysis to support your study (<strong><em>up to $10K per study, where applicable<\/em><\/strong>)<\/li>\n<li>Patient\/Family\/Donor &#8211; Researcher Partnerships (<strong><em>$1500 per patient, $500 in remuneration, and $1000 to help support patient\/family\/donor involvement in our Annual meeting<\/em><\/strong>)<\/li>\n<li>Trainee Support (<strong><em>$1000 per trainee to support attendance at the CDTRP annual meeting. Please note that trainees must be enrolled and participate in our Trainee program to be eligible for travel funds.<\/em><\/strong>)<\/li>\n<li>Data Safety Monitoring Board (DSMB)<\/li>\n<li>Access to Biomarker, Immune\u00a0Monitoring and Artificial Intelligence expertise<\/li>\n<li>CDTRP Central Management Team and Communication Resources<\/li>\n<li>Small Meeting Support and Knowledge Dissemination<\/li>\n<li>Development and production of\u00a0FAST FACTS as part of your knowledge translation plan<\/li>\n<\/ul>\n<p>In order to request support from the CDTRP, please <a href=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2020\/01\/CDTRP-support-Application-Form-GENERAL-FINAL.docx\">complete a support request form<\/a> and return it to Melanie (<a href=\"mailto:mdieude@cntrp.ca\">mdieude@cntrp.ca<\/a><u>)<\/u> and cc Leanne (<a href=\"mailto:lstalker@cdtrp.ca\">lstalker@cdtrp.ca<\/a>).<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":3294,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,75],"tags":[],"class_list":["post-3331","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general","category-featured"],"_links":{"self":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/3331"}],"collection":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/comments?post=3331"}],"version-history":[{"count":23,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/3331\/revisions"}],"predecessor-version":[{"id":3392,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/3331\/revisions\/3392"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/media\/3294"}],"wp:attachment":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/media?parent=3331"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/categories?post=3331"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/tags?post=3331"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}