{"id":32799,"date":"2025-08-09T20:37:00","date_gmt":"2025-08-10T00:37:00","guid":{"rendered":"https:\/\/cdtrp.ca\/?p=32799"},"modified":"2025-08-12T11:23:32","modified_gmt":"2025-08-12T15:23:32","slug":"organ-donation-and-transplant-research-foundation-of-bc-cdtrp-venture-grant-dr-daljeet-chahal","status":"publish","type":"post","link":"https:\/\/cdtrp.ca\/en\/organ-donation-and-transplant-research-foundation-of-bc-cdtrp-venture-grant-dr-daljeet-chahal\/","title":{"rendered":"Organ Donation and Transplant Research Foundation of BC\/CDTRP Venture Grant: Dr. Daljeet Chahal"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-dropshadow imageframe-1 hover-type-none\" style=\"-webkit-box-shadow: 3px 3px 7px rgba(0,0,0,0.3);box-shadow: 3px 3px 7px rgba(0,0,0,0.3);\"><img decoding=\"async\" width=\"1600\" height=\"900\" title=\"Chahal\" src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2.png\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2.png\" alt class=\"lazyload img-responsive wp-image-32876\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271600%27%20height%3D%27900%27%20viewBox%3D%270%200%201600%20900%27%3E%3Crect%20width%3D%271600%27%20height%3D%27900%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2-200x113.png 200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2-400x225.png 400w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2-600x338.png 600w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2-800x450.png 800w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2-1200x675.png 1200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2025\/08\/Chahal-2.png 1600w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 1200px\" \/><\/span><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><\/div><div class=\"fusion-text fusion-text-1\"><p data-pm-slice=\"1 1 &#091;&#093;\"><strong>CDTRP 2025 Research Innovation Grant Competition Results<\/strong><\/p>\n<p>CDTRP is thrilled to announce the results of the <a class=\"ProsemirrorEditor-link\" href=\"https:\/\/cdtrp.ca\/en\/announcing-the-results-of-the-2025-cdtrp-research-innovation-grant-competition-11-new-projects-funded\/\">CDTRP 2025 Research Innovation Grant Competition<\/a>, made possible through our partnership with various esteemed organizations. We are proud to showcase all of the exciting projects that have been funded in this year\u2019s competition.<\/p>\n<p>We would like to extend our warmest congratulations to <strong>Dr. Daljeet Chahal<\/strong> and his team for being awarded the <strong>Organ Donation and Transplant Research Foundation of BC\/CDTRP Venture Grant<\/strong>. We wish them all the best as they embark on their innovative project!<\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-double sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;border-bottom-width:1px;\"><\/div><\/div><style type='text\/css'>.reading-box-container-1 .element-bottomshadow:before,.reading-box-container-1 .element-bottomshadow:after{opacity:0.7;}<\/style><div class=\"fusion-reading-box-container reading-box-container-1\" style=\"--awb-title-color:#333c4e;--awb-margin-top:0px;--awb-margin-bottom:84px;\"><div class=\"reading-box\" style=\"background-color:#f6f6f6;border-width:1px;border-color:#f6f6f6;border-left-width:3px;border-left-color:var(--primary_color);border-style:solid;\"><div class=\"reading-box-additional\">\n<p data-pm-slice=\"1 1 &#091;&#093;\"><em>\u201cWe are proud to support these bold and innovative projects that address critical gaps in organ donation and transplantation research. From improving neurologic death prediction to advancing organ viability through perfusion science and elevating patient and physician voices in kidney transplantation, each project reflects our commitment to discovery, collaboration, and meaningful impact.\u201d<\/em><\/p>\n<p><em>Rachael Durie, ODTRF Co-Chair<\/em><\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-text fusion-text-2\"><p data-pm-slice=\"1 1 &#091;&#093;\"><strong>Organ Donation and Transplant Research Foundation of BC\/CDTRP Venture Grant: Dr. Daljeet Chahal<\/strong><\/p>\n<p><strong>Project Title: <\/strong>Characterizing the Physiology of Hepatic Ischemia-Reperfusion Injury in Circulatory Death and Normothermic Regional Perfusion: A Feasibility Study<\/p>\n<p><strong>Main affiliation: <\/strong>University of British Columbia<\/p>\n<p><strong>Theme: 3 \u2013 <\/strong>Engineer and Allocate Better Grafts<\/p>\n<\/div><div class=\"fusion-text fusion-text-3\"><p><span style=\"color: #000000;\"><strong>Lay Abstract<\/strong><\/span><\/p>\n<\/div><style type='text\/css'>.reading-box-container-2 .element-bottomshadow:before,.reading-box-container-2 .element-bottomshadow:after{opacity:0.7;}<\/style><div class=\"fusion-reading-box-container reading-box-container-2\" style=\"--awb-title-color:#333c4e;--awb-margin-top:0px;--awb-margin-bottom:84px;\"><div class=\"reading-box\" style=\"background-color:#f6f6f6;border-width:1px;border-color:#f6f6f6;border-left-width:3px;border-left-color:var(--primary_color);border-style:solid;\"><div class=\"reading-box-additional\">\n<p data-pm-slice=\"1 1 &#091;&#093;\">The need for liver transplantation to treat severe liver diseases is growing in Canada, yet the number of available donor organs remains insufficient. Donor livers can come from patients who have suffered brain death, or cardiac death. Donation after cardiac death is a relatively new development. Although cardiac death donors have resulted in increased organ availability, livers from cardiac death donors are more prone to complications associated with low oxygen levels during donation. Studies suggest that a promising technique called normothermic regional perfusion (NRP) may help restore oxygen levels and improve the quality of these livers before they are transplanted. Unfortunately, we don&#8217;t fully understand how NRP affects the liver&#8217;s normal functions during this process. This research project aims to investigate the specific changes that occur in the liver during NRP. To start, we will investigate how decreased oxygen levels correlate with donor liver inflammation, how NRP impacts donor liver inflammation, and if any change in inflammation leads to an improvement in donor liver quality. By gaining a better understanding of these changes, we hope to discover ways to further enhance the quality of transplanted livers and improve the outcomes for patients. Throughout this research, we will involve patients, families, and donors to ensure that our work addresses what is most important to them.<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-double sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;border-bottom-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-4\"><h5 style=\"text-align: center;\"><a href=\"https:\/\/cdtrp.ca\/en\/announcing-the-results-of-the-2025-cdtrp-research-innovation-grant-competition-11-new-projects-funded\/\"><strong>View the results of the 2025 CDTRP Research Innovation Grant Competition.<\/strong><\/a><\/h5>\n<h5 class=\"fusion-responsive-typography-calculated\" style=\"text-align: center;\" data-fontsize=\"20\" data-lineheight=\"30px\"><a href=\"https:\/\/cdtrp.ca\/en\/cdtrp-innovation-grant-winners\/\">View past CDTRP Innovation Grants recipients here.<\/a><\/h5>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":8,"featured_media":32876,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,75],"tags":[],"class_list":["post-32799","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general","category-featured"],"_links":{"self":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/32799"}],"collection":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/comments?post=32799"}],"version-history":[{"count":3,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/32799\/revisions"}],"predecessor-version":[{"id":32886,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/32799\/revisions\/32886"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/media\/32876"}],"wp:attachment":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/media?parent=32799"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/categories?post=32799"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/tags?post=32799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}