{"id":24987,"date":"2023-07-25T07:26:01","date_gmt":"2023-07-25T12:26:01","guid":{"rendered":"https:\/\/cdtrp.ca\/?p=24987"},"modified":"2023-07-26T11:38:27","modified_gmt":"2023-07-26T16:38:27","slug":"innovation-grant-2023-mamatha-bhat","status":"publish","type":"post","link":"https:\/\/cdtrp.ca\/en\/innovation-grant-2023-mamatha-bhat\/","title":{"rendered":"CDTRP UHN Research Innovation Grant: Dr. Mamatha Bhat"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-dropshadow imageframe-1 hover-type-none\" style=\"-webkit-box-shadow: 3px 3px 7px rgba(0,0,0,0.3);box-shadow: 3px 3px 7px rgba(0,0,0,0.3);\"><img decoding=\"async\" width=\"1024\" height=\"576\" title=\"CDTRP Innovation Grant 2023 &#8211; Bhat\" src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat.png\" data-orig-src=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat-1024x576.png\" alt class=\"lazyload img-responsive wp-image-24976\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271600%27%20height%3D%27900%27%20viewBox%3D%270%200%201600%20900%27%3E%3Crect%20width%3D%271600%27%20height%3D%27900%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat-200x113.png 200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat-400x225.png 400w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat-600x338.png 600w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat-800x450.png 800w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat-1200x675.png 1200w, https:\/\/cdtrp.ca\/wp-content\/uploads\/2023\/07\/CDTRP-Innovation-Grant-2023-Bhat.png 1600w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 1200px\" \/><\/span><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><\/div><div class=\"fusion-text fusion-text-1\"><h4 data-pm-slice=\"1 1 &#091;&#093;\"><strong>CDTRP 2023 Research Innovation Grant Competition Results<\/strong><\/h4>\n<p class=\"sc-98942fc5-0 JcSiB\" data-testid=\"youchat-text\">CDTRP is thrilled to announce the results of the <a href=\"https:\/\/cdtrp.ca\/en\/support-for-research\/cdtrp-innovation-grant-competition\/\">CDTRP 2023 Research Innovation Grant Competition<\/a>, made possible through our partnership with various esteemed organizations. We are proud to showcase all of the exciting projects that have been funded in this year&#8217;s competition.<\/p>\n<p class=\"sc-98942fc5-0 JcSiB\" data-testid=\"youchat-text\">We would like to extend our warmest congratulations to <strong>Dr. Mamatha Bhat<\/strong> and her team for being awarded the <strong>CDTRP UHN Research Innovation Grant<\/strong>. We wish them all the best as they embark on their innovative project!<b><\/b><\/p>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-double sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;border-bottom-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-2\"><h5 data-pm-slice=\"1 1 &#091;&#093;\" data-fontsize=\"24\" data-lineheight=\"36px\"><strong>CDTRP UHN Research Innovation Grant: Dr. Mamatha Bhat <\/strong><\/h5>\n<p data-pm-slice=\"1 1 &#091;&#093;\"><strong>Development of a Machine Learning Tool for Non-invasive Diagnosis of Liver Graft Pathology\u00a0<\/strong><\/p>\n<ul>\n<li><strong>Main affiliation:<\/strong> University Health Network<\/li>\n<li><strong>Theme 5<\/strong> &#8211; Restore Long-Term Health<\/li>\n<\/ul>\n<h6><strong>Lay abstract<\/strong><\/h6>\n<blockquote>\n<p data-pm-slice=\"1 1 &#091;&#093;\"><strong>Background &amp; Importance:<\/strong> Liver transplantation has been lifesaving for patients with end-stage liver disease. Yet, the new liver or graft can develop inflammation for different reasons. A liver biopsy is the current standard of method to identify the cause of inflammation. A liver biopsy is a surgical procedure and is associated with risks of infection. There is often a delay in performing a liver biopsy due to various reasons, such as availability. Procedural delays and repeated episodes of inflammation can lead to chronic inflammation. This results in permanent liver injury and jeopardizes the lifespan of this precious gift.<\/p>\n<p><strong>Proposed Innovative Solution:<\/strong> We have developed a Machine learning (ML) tool to predict the cause of liver graft inflammation. This tool is currently limited to NASH and rejection. We want to improve it by including biliary obstruction. We will determine how well it performs in identifying the cause of liver inflammation.<\/p>\n<p><strong>Expected Outcomes:<\/strong> This study will show the potential of a ML tool to diagnose the cause of liver inflammation. Care providers of patients will be able to use the predictions made to guide decisions. With a safer and faster tool to diagnose liver inflammation, we can extend the lifespan of both the liver graft and its recipient.<\/p>\n<\/blockquote>\n<\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:30px;margin-bottom:30px;width:100%;\"><div class=\"fusion-separator-border sep-double sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;border-color:#e0dede;border-top-width:1px;border-bottom-width:1px;\"><\/div><\/div><div class=\"fusion-text fusion-text-3\"><h5 style=\"text-align: center;\"><a href=\"https:\/\/cdtrp.ca\/en\/innovation-grant-2023-results\/\"><strong>View the results of the 2023 CDTRP Research Innovation Grant Competition.<\/strong><\/a><\/h5>\n<h5 class=\"fusion-responsive-typography-calculated\" style=\"text-align: center;\" data-fontsize=\"20\" data-lineheight=\"30px\"><a href=\"https:\/\/cdtrp.ca\/en\/cdtrp-innovation-grant-winners\/\">View past CDTRP Innovation Grants recipients here.<\/a><\/h5>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":24976,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,75],"tags":[],"class_list":["post-24987","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general","category-featured"],"_links":{"self":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/24987"}],"collection":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/comments?post=24987"}],"version-history":[{"count":2,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/24987\/revisions"}],"predecessor-version":[{"id":25054,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/posts\/24987\/revisions\/25054"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/media\/24976"}],"wp:attachment":[{"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/media?parent=24987"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/categories?post=24987"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdtrp.ca\/en\/wp-json\/wp\/v2\/tags?post=24987"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}